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Orai1 downregulation causes proliferation reduction and cell cycle arrest via inactivation of the Ras-NF-κB signaling pathway in osteoblasts

BACKGROUND: The purpose of this study was to determine the role of Orai1 in the regulation of the proliferation and cell cycle of osteoblasts. METHODS: The expression of Orai1 was inhibited by Orai1 small interfering RNA (siRNA) in MC3T3-E1 cells. Following Orai1 downregulation, cell proliferation a...

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Detalles Bibliográficos
Autores principales:	Guo, Yunshan, Fan, Jinzhu, Liu, Shuguang, Hao, Dingjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996479/ https://www.ncbi.nlm.nih.gov/pubmed/35410330 http://dx.doi.org/10.1186/s12891-022-05311-y

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