Evaluation of photoreceptor-directed fibroblasts derived from retinitis pigmentosa patients with defects in the EYS gene: a possible cost-effective cellular model for mechanism-oriented drug

BACKGROUND: The most common gene responsible for autosomal recessive retinitis pigmentosa (RP) is EYS. The manner of decay of genetically defective EYS gene transcripts varies depending on the type of mutation using our cellular model, which consists of induced photoreceptor-directed fibroblasts fro...

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Detalles Bibliográficos
Autores principales: Rai, Dilip, Iwanami, Masaki, Takahashi, Yoriko, Komuta, Yukari, Aoi, Noriyuki, Umezawa, Akihiro, Seko, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996485/
https://www.ncbi.nlm.nih.gov/pubmed/35410372
http://dx.doi.org/10.1186/s13287-022-02827-x

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