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Vaspin promotes chondrogenic differentiation of BMSCs via Akt activation in osteoarthritis

BACKGROUND: The aim of this study was to investigate the role of Vaspin on the chondrogenic differentiation of bone mesenchymal stem cells (BMSCs), and its effect on chondrocyte survival and ECM secretion. We also assessed whether the Akt activation participates in these processes. METHODS: In vivo,...

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Detalles Bibliográficos
Autores principales: Wang, Junfeng, Zhang, Keshi, Zhang, Shaolong, Guan, Zhenpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996515/
https://www.ncbi.nlm.nih.gov/pubmed/35410202
http://dx.doi.org/10.1186/s12891-022-05295-9