Cargando…

Vaspin promotes chondrogenic differentiation of BMSCs via Akt activation in osteoarthritis

BACKGROUND: The aim of this study was to investigate the role of Vaspin on the chondrogenic differentiation of bone mesenchymal stem cells (BMSCs), and its effect on chondrocyte survival and ECM secretion. We also assessed whether the Akt activation participates in these processes. METHODS: In vivo,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Junfeng, Zhang, Keshi, Zhang, Shaolong, Guan, Zhenpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996515/ https://www.ncbi.nlm.nih.gov/pubmed/35410202 http://dx.doi.org/10.1186/s12891-022-05295-9

Ejemplares similares

Dynamic mechanical loading facilitated chondrogenic differentiation of rabbit BMSCs in collagen scaffolds
por: Cao, Wanxu, et al.
Publicado: (2019)

Icariin accelerates cartilage defect repair by promoting chondrogenic differentiation of BMSCs under conditions of oxygen‐glucose deprivation
por: Tang, Wang, et al.
Publicado: (2021)

Transfection of the IHH gene into rabbit BMSCs in a simulated microgravity environment promotes chondrogenic differentiation and inhibits cartilage aging
por: Liu, Peng-Cheng, et al.
Publicado: (2016)

E7 Peptide Enables BMSC Adhesion and Promotes Chondrogenic Differentiation of BMSCs Via the LncRNA H19/miR675 Axis
por: Shi, Weili, et al.
Publicado: (2023)

Leonurine Promotes the Osteoblast Differentiation of Rat BMSCs by Activation of Autophagy via the PI3K/Akt/mTOR Pathway
por: Zhao, Bingkun, et al.
Publicado: (2021)

Programmed cell death 5 transgenic mice attenuates adjuvant induced arthritis by 2 modifying the T lymphocytes balance
por: Yuan, Feng, et al.
Publicado: (2017)

Murine and Chinese cobra venom-derived nerve growth factor stimulate chondrogenic differentiation of BMSCs in vitro: A comparative study
por: Miao, Zhikang, et al.
Publicado: (2018)

Murine and Chinese cobra venom-derived nerve growth factor stimulate chondrogenic differentiation of BMSCs in vitro: A comparative study
por: Miao, Zhikang, et al.
Publicado: (2021)

Icariin promotes osteogenic differentiation of BMSCs by upregulating BMAL1 expression via BMP signaling
por: Huang, Zengfa, et al.
Publicado: (2020)

Sodium Selenite Improves The Therapeutic Effect Of BMSCs Via Promoting The Proliferation And Differentiation, Thereby Promoting The Hematopoietic Factors
por: Yan, Dongmei, et al.
Publicado: (2019)

Ubiquitination of ASCL1 mediates CD47 transcriptional activation of the AKT signaling pathway, and glycolysis promotes osteogenic differentiation of hBMSCs
por: Zhang, Jimei, et al.
Publicado: (2023)

The osteoarthritis-associated gene PAPSS2 promotes differentiation and matrix formation in ATDC5 chondrogenic cells
por: Fan, Liying, et al.
Publicado: (2018)

Factors affecting osteogenesis and chondrogenic differentiation of mesenchymal stem cells in osteoarthritis
por: Peng, Yi, et al.
Publicado: (2023)

Effects of vaspin on pancreatic β cell secretion via PI3K/Akt and NF-κB signaling pathways
por: Liu, Shiwei, et al.
Publicado: (2017)

Icariin Promotes the Migration of BMSCs In Vitro and In Vivo via the MAPK Signaling Pathway
por: Jiao, Feng, et al.
Publicado: (2018)

Decreased expression of GEM in osteoarthritis cartilage regulates chondrogenic differentiation via Wnt/β-catenin signaling
por: Gan, Lu, et al.
Publicado: (2023)

Hyperoside ameliorates periodontitis in rats by promoting osteogenic differentiation of BMSCs via activation of the NF‐κB pathway
por: Xu, Tao, et al.
Publicado: (2020)

miR-129-5p Promotes Osteogenic Differentiation of BMSCs and Bone Regeneration via Repressing Dkk3
por: Zhao, Changming, et al.
Publicado: (2021)

Immunomodulatory PEG-CRGD Hydrogels Promote Chondrogenic Differentiation of PBMSCs
por: Yang, Meng, et al.
Publicado: (2022)

Moderate SMFs attenuate bone loss in mice by promoting directional osteogenic differentiation of BMSCs
por: Chen, Guilin, et al.
Publicado: (2020)

Neural cell adhesion molecule regulates chondrocyte hypertrophy in chondrogenic differentiation and experimental osteoarthritis
por: Cheng, Bin‐Feng, et al.
Publicado: (2019)

Circ_0136474 and MMP‐13 suppressed cell proliferation by competitive binding to miR‐127‐5p in osteoarthritis
por: Li, Zhao, et al.
Publicado: (2019)

Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs
por: Wang, Chenglong, et al.
Publicado: (2022)

Activating Wnt/β-Catenin Signaling in Osteocytes Promotes Osteogenic Differentiation of BMSCs through BMP-7
por: Zhang, Yining, et al.
Publicado: (2022)

Evaluation of Tissue Expression of Vaspin and Serum Vaspin Concentration as a Prognostic and Risk Factor in Endometrial Cancer
por: Kozłowski, Mateusz, et al.
Publicado: (2022)

Suppression of CRLF1 promotes the chondrogenic differentiation of bone marrow-derived mesenchymal stem and protects cartilage tissue from damage in osteoarthritis via activation of miR-320
por: Xu, Hao, et al.
Publicado: (2021)

Promoting proliferation and differentiation of BMSCs by green tea polyphenols functionalized porous calcium phosphate
por: Zhou, Kang, et al.
Publicado: (2018)

Icariin-Loaded Hydrogel Regulates Bone Marrow Mesenchymal Stem Cell Chondrogenic Differentiation and Promotes Cartilage Repair in Osteoarthritis
por: Zhu, Yuefeng, et al.
Publicado: (2022)

Effects of Vaspin on Insulin Resistance in Rats and Underlying Mechanisms
por: Liu, Shiwei, et al.
Publicado: (2018)

Role of Vaspin in Human Eating Behaviour
por: Breitfeld, Jana, et al.
Publicado: (2013)

Adipokines Vaspin and Visfatin in Obese Children
por: Salama, Hassan M., et al.
Publicado: (2015)

BMSCs promote the differentiation of NSCs into oligodendrocytes via mediating Id2 and Olig expression through BMP/Smad signaling pathway
por: Song, Peiwen, et al.
Publicado: (2018)

Fabrication of 3D-Printed Interpenetrating Hydrogel Scaffolds for Promoting Chondrogenic Differentiation
por: Guan, Jian, et al.
Publicado: (2021)

Simvastatin improves the homing of BMSCs via the PI3K/AKT/miR‐9 pathway
por: Bing, Weidong, et al.
Publicado: (2016)

Low-dose IL-34 has no effect on osteoclastogenesis but promotes osteogenesis of hBMSCs partly via activation of the PI3K/AKT and ERK signaling pathways
por: Xu, Jianxiang, et al.
Publicado: (2021)

HPF Modulates the Differentiation of BMSCs into HLCs and Promotes the Recovery of Acute Liver Injury in Mice
por: Yang, Bin, et al.
Publicado: (2023)

ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs
por: Peng, Hui, et al.
Publicado: (2020)

Significance of vaspin in obstructive sleep apnea-hypopnea syndrome
por: PAN, ZHE, et al.
Publicado: (2016)

Irisin enhances chondrogenic differentiation of human mesenchymal stem cells via Rap1/PI3K/AKT axis
por: Chen, Taiqiu, et al.
Publicado: (2022)

Alpinetin alleviates osteoporosis by promoting osteogenic differentiation in BMSCs by triggering autophagy via PKA/mTOR/ULK1 signaling
por: Zeng, Chenying, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u5ccvj5ha7lrg684hsu3b862i4