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Inferring mammalian tissue-specific regulatory conservation by predicting tissue-specific differences in open chromatin

BACKGROUND: Evolutionary conservation is an invaluable tool for inferring functional significance in the genome, including regions that are crucial across many species and those that have undergone convergent evolution. Computational methods to test for sequence conservation are dominated by algorit...

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Detalles Bibliográficos
Autores principales:	Kaplow, Irene M., Schäffer, Daniel E., Wirthlin, Morgan E., Lawler, Alyssa J., Brown, Ashley R., Kleyman, Michael, Pfenning, Andreas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996547/ https://www.ncbi.nlm.nih.gov/pubmed/35410163 http://dx.doi.org/10.1186/s12864-022-08450-7

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