Identification of distinct slow mode of reversible adaptation of pancreatic ductal adenocarcinoma to the prolonged acidic pH microenvironment

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic neoplasm with high metastatic potential and poor clinical outcome. Like other solid tumors, PDAC in the early stages is often asymptomatic, and grows very slowly under a distinct acidic pHe (extracellular pH) microenvi...

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Detalles Bibliográficos
Autores principales: Wu, Tzu-Chin, Liao, Chien-Yu, Lu, Wei-Chien, Chang, Chuang-Rung, Tsai, Fang-Yu, Jiang, Shih-Sheng, Chen, Tsung-Hsien, Lin, Kurt Ming-Chao, Chen, Li-Tzong, Chang, Wun-Shaing Wayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996570/
https://www.ncbi.nlm.nih.gov/pubmed/35410237
http://dx.doi.org/10.1186/s13046-022-02329-x

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