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Accurate prediction of molecular targets using a self-supervised image representation learning framework

The clinical efficacy and safety of a drug is determined by its molecular targets in the human proteome. However, proteome-wide evaluation of all compounds in human, or even animal models, is challenging. In this study, we present an unsupervised pre-training deep learning framework, termed ImageMol...

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Detalles Bibliográficos
Autores principales:	Zeng, Xiangxiang, Xiang, Hongxin, Yu, Linhui, Wang, Jianmin, Li, Kenli, Nussinov, Ruth, Cheng, Feixiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996628/ https://www.ncbi.nlm.nih.gov/pubmed/35411337 http://dx.doi.org/10.21203/rs.3.rs-1477870/v1

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