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Long noncoding RNA PVT1 promotes chondrocyte extracellular matrix degradation by acting as a sponge for miR-140 in IL-1β-stimulated chondrocytes

BACKGROUND: Osteoarthritis (OA) is a common degenerative joint disease, and chondrocyte extracellular matrix (ECM) degradation is one vital pathological feature of OA. Long noncoding RNA (lncRNA), a new kind of gene regulator, plays an important role in pathogenesis of many diseases like OA. Recent...

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Detalles Bibliográficos
Autores principales:	Yao, Nan, Peng, Sha, Wu, Huai, Liu, Wengang, Cai, Dake, Huang, Dane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996637/ https://www.ncbi.nlm.nih.gov/pubmed/35399100 http://dx.doi.org/10.1186/s13018-022-03114-4

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