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Daily Practice Assessment of KRAS Status in NSCLC Patients: A New Challenge for the Thoracic Pathologist Is Right around the Corner

SIMPLE SUMMARY: RAS mutation is the most frequent oncogenic alteration in human cancers and KRAS is the most frequently mutated, notably in non-small cell lung carcinomas (NSCLC). Various attempts to inhibit KRAS in the past were unsuccessful in these latter tumors. However, recently, several small...

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Detalles Bibliográficos
Autores principales: Bontoux, Christophe, Hofman, Véronique, Brest, Patrick, Ilié, Marius, Mograbi, Baharia, Hofman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996900/
https://www.ncbi.nlm.nih.gov/pubmed/35406400
http://dx.doi.org/10.3390/cancers14071628