TERT Expression in Wilms Tumor Is Regulated by Promoter Mutation or Hypermethylation, WT1, and N-MYC

SIMPLE SUMMARY: The telomerase enzyme adds repetitive genetic sequences to the ends of chromosomes called telomeres to prevent cellular senescence. Gain of telomerase function is one of the hallmarks of human cancer. The telomerase protein is coded by the gene TERT and increased TERT RNA levels have...

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Detalles Bibliográficos
Autores principales: Jablonowski, Carolyn M., Gil, Hyea Jin, Pinto, Emilia M., Pichavaram, Prahalathan, Fleming, Andrew M., Clay, Michael R., Hu, Dongli, Morton, Christopher L., Pruett-Miller, Shondra M., Hansen, Baranda S., Chen, Xiang, Jones, Karissa M. Dieseldorff, Liu, Yanling, Ma, Xiaotu, Yang, Jun, Davidoff, Andrew M., Zambetti, Gerard P., Murphy, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996936/
https://www.ncbi.nlm.nih.gov/pubmed/35406427
http://dx.doi.org/10.3390/cancers14071655

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