Inhibiting Endothelin Receptors with Macitentan Strengthens the Bone Protective Action of RANKL Inhibition and Reduces Metastatic Dissemination in Osteosarcoma

SIMPLE SUMMARY: The efficacy of current osteosarcoma therapy is diminished by two adverse events, namely resistance to chemotherapy and metastatic dissemination. In recent decades, research has been devoted to reducing these adverse events. Inhibiting bone resorption has shown promising effects on m...

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Detalles Bibliográficos
Autores principales: Muñoz-Garcia, Javier, Vargas-Franco, Jorge William, Royer, Bénédicte Brounais-Le, Cochonneau, Denis, Amiaud, Jérôme, Heymann, Marie-Françoise, Heymann, Dominique, Lézot, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997105/
https://www.ncbi.nlm.nih.gov/pubmed/35406536
http://dx.doi.org/10.3390/cancers14071765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997105/
https://www.ncbi.nlm.nih.gov/pubmed/35406536
http://dx.doi.org/10.3390/cancers14071765

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