Cargando…

Unravelling Prostate Cancer Heterogeneity Using Spatial Approaches to Lipidomics and Transcriptomics

SIMPLE SUMMARY: Prostate cancer is a heterogenous disease in terms of disease aggressiveness and therapy response, leading to dilemmas in treatment decisions. This heterogeneity reflects the multifocal nature of prostate cancer and its diversity in cellular and molecular composition, necessitating s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mutuku, Shadrack M., Spotbeen, Xander, Trim, Paul J., Snel, Marten F., Butler, Lisa M., Swinnen, Johannes V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997139/ https://www.ncbi.nlm.nih.gov/pubmed/35406474 http://dx.doi.org/10.3390/cancers14071702

Ejemplares similares

Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry
por: Mutuku, Shadrack M., et al.
Publicado: (2019)

Stable Isotope-Labeled Lipidomics to Unravel the Heterogeneous Development Lipotoxicity
por: Shih, Lu-Min, et al.
Publicado: (2018)

Integration of lipidomics and transcriptomics unravels aberrant lipid metabolism and defines cholesteryl oleate as potential biomarker of prostate cancer
por: Li, Jia, et al.
Publicado: (2016)

Spatial Systems Lipidomics Reveals Nonalcoholic Fatty Liver Disease Heterogeneity
por: Ščupáková, Klára, et al.
Publicado: (2018)

Lymphoma Heterogeneity Unraveled by Single-Cell Transcriptomics
por: Ysebaert, Loic, et al.
Publicado: (2021)

Spatially Annotated Single Cell Sequencing for Unraveling Intratumor Heterogeneity
por: Smit, Myrthe M., et al.
Publicado: (2022)

Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity
por: Berglund, Emelie, et al.
Publicado: (2018)

Lipogenic effects of androgen signaling in normal and malignant prostate
por: Mah, Chui Yan, et al.
Publicado: (2020)

Development of a Laser Microdissection-Coupled Quantitative Shotgun Lipidomic Method to Uncover Spatial Heterogeneity
por: Varga-Zsíros, Vanda, et al.
Publicado: (2023)

Integrative lipidomic and transcriptomic study unravels the therapeutic effects of saikosaponins A and D on non-alcoholic fatty liver disease
por: Li, Xiaojiaoyang, et al.
Publicado: (2021)

Spatial Transcriptomics for Tumor Heterogeneity Analysis
por: Li, Qiongyu, et al.
Publicado: (2022)

Serum lipidome unravels a diagnostic potential in bile acid diarrhoea
por: Lewinska, Monika, et al.
Publicado: (2023)

Spatial lipidomics of fresh-frozen spines
por: Bender, Kayle J., et al.
Publicado: (2023)

Modulation of Plasma Lipidomic Profiles in Metastatic Castration-Resistant Prostate Cancer by Simvastatin
por: Mak, Blossom, et al.
Publicado: (2022)

ONION: Functional Approach for Integration of Lipidomics and Transcriptomics Data
por: Piwowar, Monika, et al.
Publicado: (2015)

Single-cell Transcriptomic Architecture Unraveling the Complexity of Tumor Heterogeneity in Distal Cholangiocarcinoma
por: Li, Hongguang, et al.
Publicado: (2022)

Determination of the Heterogeneity of Intramuscular Fat and Visceral Adipose Tissue From Dezhou Donkey by Lipidomics and Transcriptomics Profiling
por: Li, Mengmeng, et al.
Publicado: (2021)

Lipidomics Unravels the Role of Leaf Lipids in Thyme Plant Response to Drought Stress
por: Moradi, Parviz, et al.
Publicado: (2017)

Unraveling the Mechanisms by Which Calpain Inhibition Prevents Heart Failure Development
por: Wehrens, Xander H.T.
Publicado: (2018)

Unraveling Spatial Gene Associations with SEAGAL: a Python Package for Spatial Transcriptomics Data Analysis and Visualization
por: Wang, Linhua, et al.
Publicado: (2023)

Unravelling spatial gene associations with SEAGAL: a Python package for spatial transcriptomics data analysis and visualization
por: Wang, Linhua, et al.
Publicado: (2023)

Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of tissue heterogeneity on genomic signatures
por: Figiel, Sandy, et al.
Publicado: (2023)

Inference on spatial heterogeneity in tumor microenvironment using spatial transcriptomics data
por: Biswas, Antara, et al.
Publicado: (2022)

Unraveling Heterogeneity in Transcriptome and Its Regulation Through Single-Cell Multi-Omics Technologies
por: Xing, Qiao Rui, et al.
Publicado: (2020)

Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae
por: Haribowo, A. Galih, et al.
Publicado: (2019)

Is the eye a window to the brain in Sanfilippo syndrome?
por: Beard, Helen, et al.
Publicado: (2020)

Transcriptomic and Lipidomic Analysis of Lipids in Forsythia suspensa
por: Wu, Bei, et al.
Publicado: (2021)

SMASH: Scalable Method for Analyzing Spatial Heterogeneity of genes in spatial transcriptomics data
por: Seal, Souvik, et al.
Publicado: (2023)

SMASH: Scalable Method for Analyzing Spatial Heterogeneity of genes in spatial transcriptomics data
por: Seal, Souvik, et al.
Publicado: (2023)

Lipidomics as a Diagnostic Tool for Prostate Cancer
por: Buszewska-Forajta, Magdalena, et al.
Publicado: (2021)

Unraveling Macrophage Heterogeneity in Erythroblastic Islands
por: Seu, Katie Giger, et al.
Publicado: (2017)

Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency
por: Evers, Bret M., et al.
Publicado: (2017)

Heterogeneity of lipidomic profiles among lung cancer subtypes of patients
por: Lv, Jiapei, et al.
Publicado: (2018)

Patients with Bacterial Sepsis Are Heterogeneous with Regard to Their Systemic Lipidomic Profiles
por: Mosevoll, Knut Anders, et al.
Publicado: (2022)

Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer
por: Mak, Blossom, et al.
Publicado: (2022)

Assessing heterogeneity in spatial data using the HTA index with applications to spatial transcriptomics and imaging
por: Levy-Jurgenson, Alona, et al.
Publicado: (2021)

Unraveling transcriptome dynamics in human spermatogenesis
por: Jan, Sabrina Z., et al.
Publicado: (2017)

Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer
por: Wyatt, Alexander W, et al.
Publicado: (2014)

Unravelling the Spatial and Temporal Plasticity of Eelgrass Meadows
por: Bertelli, Chiara M., et al.
Publicado: (2021)

Unravelling the Heterogeneity of Non Insulin Dependent Diabetes
por: Pearson, Ewan R, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_ucfgr3rs5bqdfjn8mnaal2o62f