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The Emerging Role of E3 Ubiquitin Ligase SMURF2 in the Regulation of Transcriptional Co-Repressor KAP1 in Untransformed and Cancer Cells and Tissues

SIMPLE SUMMARY: KAP1 plays an essential role in different molecular and cellular processes central to carcinogenesis, disease progression, and treatment response, revealing both tumor promoting and anticancer functions. The mechanisms that control the steady-state levels of KAP1 and its protein abun...

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Detalles Bibliográficos
Autores principales: Shah, Pooja Anil, Boutros-Suleiman, Sandy, Emanuelli, Andrea, Paolini, Biagio, Levy-Cohen, Gal, Blank, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997158/
https://www.ncbi.nlm.nih.gov/pubmed/35406379
http://dx.doi.org/10.3390/cancers14071607