SMYD3 Promotes Cell Cycle Progression by Inducing Cyclin D3 Transcription and Stabilizing the Cyclin D1 Protein in Medulloblastoma

SIMPLE SUMMARY: Medulloblastoma is the most common malignant pediatric brain tumor and is classified into four molecular subgroups: Wnt, Shh, Group 3, and Group 4. Of these subgroups, patients with Myc+ Group 3 MB have the worst prognosis. Using an RNAi functional genomic screen, we identified the l...

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Detalles Bibliográficos
Autores principales: Asuthkar, Swapna, Venkataraman, Sujatha, Avilala, Janardhan, Shishido, Katherine, Vibhakar, Rajeev, Veo, Bethany, Purvis, Ian J., Guda, Maheedhara R., Velpula, Kiran K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997160/
https://www.ncbi.nlm.nih.gov/pubmed/35406445
http://dx.doi.org/10.3390/cancers14071673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997160/
https://www.ncbi.nlm.nih.gov/pubmed/35406445
http://dx.doi.org/10.3390/cancers14071673

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