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Proteomic and Transcriptomic Profiling Reveals Mitochondrial Oxidative Phosphorylation as Therapeutic Vulnerability in Androgen Receptor Pathway Active Prostate Tumors

SIMPLE SUMMARY: Metastatic prostate cancer (PC) is the second leading cause of cancer deaths in males. The lack of preclinical models and molecular characterization for advanced stage PC is a key barrier in understanding the aggressive subsets androgen receptor (AR) pathway active or AR-null castrat...

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Detalles Bibliográficos
Autores principales: Xue, Caroline, Corey, Eva, Gujral, Taranjit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997167/
https://www.ncbi.nlm.nih.gov/pubmed/35406510
http://dx.doi.org/10.3390/cancers14071739

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