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Association between Socioeconomic Status and Homeostasis Model Assessment-Insulin Resistance Index and Mediating Variables at the First Trimester of Pregnancy
BACKGROUND: Some studies have shown that Socioeconomic Status (SES) is positively related to insulin resistance among different population groups, except for pregnant women. Therefore, we examined the relationship between SES and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) index as wel...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997184/ https://www.ncbi.nlm.nih.gov/pubmed/35419260 http://dx.doi.org/10.4103/ijnmr.ijnmr_451_20 |
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author | Mohammadi, Raziyeh Goodarzi-Khoigani, Masoomeh Allameh, Zahra Mazloomy Mahmoodabad, Seyed Saeed Baghiani Moghadam, Mohammad Hossein Nadjarzadeh, Azadeh Mardanian, Farahnaz |
author_facet | Mohammadi, Raziyeh Goodarzi-Khoigani, Masoomeh Allameh, Zahra Mazloomy Mahmoodabad, Seyed Saeed Baghiani Moghadam, Mohammad Hossein Nadjarzadeh, Azadeh Mardanian, Farahnaz |
author_sort | Mohammadi, Raziyeh |
collection | PubMed |
description | BACKGROUND: Some studies have shown that Socioeconomic Status (SES) is positively related to insulin resistance among different population groups, except for pregnant women. Therefore, we examined the relationship between SES and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) index as well as mediating variables. MATERIALS AND METHODS: This study was performed on 138 primiparous healthy women at 6–10 weeks of pregnancy. The association between SES and HOMA-IR was analyzed by regression analysis, and mediating variables were determined by mediation analysis. RESULTS: SES score was positively correlated with HOMA-IR index [β = 0.02, t(101) = 2.20, p = 0.03, 95% CI: (0.00–0.05]. The higher percentage of mediation was related to maternal weigh (70.80%). Job activity had a protective effect on the association between SES and HOMA-IR (-62.50%). The total percentage of two mediators was 25%. CONCLUSIONS: The positive relationship between SES and (HOMA-IR) in early pregnancy may provide a way to control this condition. |
format | Online Article Text |
id | pubmed-8997184 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-89971842022-04-12 Association between Socioeconomic Status and Homeostasis Model Assessment-Insulin Resistance Index and Mediating Variables at the First Trimester of Pregnancy Mohammadi, Raziyeh Goodarzi-Khoigani, Masoomeh Allameh, Zahra Mazloomy Mahmoodabad, Seyed Saeed Baghiani Moghadam, Mohammad Hossein Nadjarzadeh, Azadeh Mardanian, Farahnaz Iran J Nurs Midwifery Res Short Communication BACKGROUND: Some studies have shown that Socioeconomic Status (SES) is positively related to insulin resistance among different population groups, except for pregnant women. Therefore, we examined the relationship between SES and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) index as well as mediating variables. MATERIALS AND METHODS: This study was performed on 138 primiparous healthy women at 6–10 weeks of pregnancy. The association between SES and HOMA-IR was analyzed by regression analysis, and mediating variables were determined by mediation analysis. RESULTS: SES score was positively correlated with HOMA-IR index [β = 0.02, t(101) = 2.20, p = 0.03, 95% CI: (0.00–0.05]. The higher percentage of mediation was related to maternal weigh (70.80%). Job activity had a protective effect on the association between SES and HOMA-IR (-62.50%). The total percentage of two mediators was 25%. CONCLUSIONS: The positive relationship between SES and (HOMA-IR) in early pregnancy may provide a way to control this condition. Wolters Kluwer - Medknow 2022-03-14 /pmc/articles/PMC8997184/ /pubmed/35419260 http://dx.doi.org/10.4103/ijnmr.ijnmr_451_20 Text en Copyright: © 2022 Iranian Journal of Nursing and Midwifery Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Short Communication Mohammadi, Raziyeh Goodarzi-Khoigani, Masoomeh Allameh, Zahra Mazloomy Mahmoodabad, Seyed Saeed Baghiani Moghadam, Mohammad Hossein Nadjarzadeh, Azadeh Mardanian, Farahnaz Association between Socioeconomic Status and Homeostasis Model Assessment-Insulin Resistance Index and Mediating Variables at the First Trimester of Pregnancy |
title | Association between Socioeconomic Status and Homeostasis Model Assessment-Insulin Resistance Index and Mediating Variables at the First Trimester of Pregnancy |
title_full | Association between Socioeconomic Status and Homeostasis Model Assessment-Insulin Resistance Index and Mediating Variables at the First Trimester of Pregnancy |
title_fullStr | Association between Socioeconomic Status and Homeostasis Model Assessment-Insulin Resistance Index and Mediating Variables at the First Trimester of Pregnancy |
title_full_unstemmed | Association between Socioeconomic Status and Homeostasis Model Assessment-Insulin Resistance Index and Mediating Variables at the First Trimester of Pregnancy |
title_short | Association between Socioeconomic Status and Homeostasis Model Assessment-Insulin Resistance Index and Mediating Variables at the First Trimester of Pregnancy |
title_sort | association between socioeconomic status and homeostasis model assessment-insulin resistance index and mediating variables at the first trimester of pregnancy |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997184/ https://www.ncbi.nlm.nih.gov/pubmed/35419260 http://dx.doi.org/10.4103/ijnmr.ijnmr_451_20 |
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