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Clinico-radiological Observations in Meconium Aspiration Syndrome

INTRODUCTION: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal. METHODS: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of MA...

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Autores principales: Lama, Susana, Mahato, Shyam Kumar, Chaudhary, Nagendra, Agrawal, Nikhil, Pathak, Santosh, Kurmi, Om Prakash, Bhatia, Baldev, Agarwal, Kailash Nath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997330/
https://www.ncbi.nlm.nih.gov/pubmed/30058634
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author Lama, Susana
Mahato, Shyam Kumar
Chaudhary, Nagendra
Agrawal, Nikhil
Pathak, Santosh
Kurmi, Om Prakash
Bhatia, Baldev
Agarwal, Kailash Nath
author_facet Lama, Susana
Mahato, Shyam Kumar
Chaudhary, Nagendra
Agrawal, Nikhil
Pathak, Santosh
Kurmi, Om Prakash
Bhatia, Baldev
Agarwal, Kailash Nath
author_sort Lama, Susana
collection PubMed
description INTRODUCTION: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal. METHODS: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of MAS in relation to gender, gestational age, mode of delivery, birth weight, Apgar score, thickness of meconium, age at admission and the immediate outcome were studied. RESULTS: Out of 584 admitted newborns (male=389; female=186) during the study period, 78 (13.4%) had meconium aspiration syndrome with male: female ratio of 1.2:1. Majority of babies admitted to NICU had thick meconium [n=52 (66.7%)]. There was no statistical significant difference in various parameters such as Apgar score at 1 and 5 minutes, respiratory distress, birth asphyxia, duration of oxygen use, MAS severity and chest x-ray in those with thick MAS compared to thin. Among all newborns with MAS, 59% (n=46) had abnormal radiological findings with over two-folds in those with thick MAS (71.7%)] compared to thin (28%). Hyperinflation (47.8%), diffuse patchy infiltration (37%), consolidation (21.7%) collapse (8.7%), right lung fissure (6.5%) and pneumothorax (8.7%) were the abnormal radiological findings seen in MAS babies. The odds of having APGAR score at 1 minute at least 7 or more was twice unlikely in those having thick meconium compared to thin (P=0.02) CONCLUSIONS: Thick meconium is relatively common with more significant abnormal radiological findings and low Apgar score.
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spelling pubmed-89973302022-05-06 Clinico-radiological Observations in Meconium Aspiration Syndrome Lama, Susana Mahato, Shyam Kumar Chaudhary, Nagendra Agrawal, Nikhil Pathak, Santosh Kurmi, Om Prakash Bhatia, Baldev Agarwal, Kailash Nath JNMA J Nepal Med Assoc Original Article INTRODUCTION: To understand and report the prevalence of meconium aspiration syndrome and the clinico-radiological features in a tertiary care hospital of western Nepal. METHODS: An observational study carried out for a year in 2014-15 in all babies with MAS. Clinical and radiological profiles of MAS in relation to gender, gestational age, mode of delivery, birth weight, Apgar score, thickness of meconium, age at admission and the immediate outcome were studied. RESULTS: Out of 584 admitted newborns (male=389; female=186) during the study period, 78 (13.4%) had meconium aspiration syndrome with male: female ratio of 1.2:1. Majority of babies admitted to NICU had thick meconium [n=52 (66.7%)]. There was no statistical significant difference in various parameters such as Apgar score at 1 and 5 minutes, respiratory distress, birth asphyxia, duration of oxygen use, MAS severity and chest x-ray in those with thick MAS compared to thin. Among all newborns with MAS, 59% (n=46) had abnormal radiological findings with over two-folds in those with thick MAS (71.7%)] compared to thin (28%). Hyperinflation (47.8%), diffuse patchy infiltration (37%), consolidation (21.7%) collapse (8.7%), right lung fissure (6.5%) and pneumothorax (8.7%) were the abnormal radiological findings seen in MAS babies. The odds of having APGAR score at 1 minute at least 7 or more was twice unlikely in those having thick meconium compared to thin (P=0.02) CONCLUSIONS: Thick meconium is relatively common with more significant abnormal radiological findings and low Apgar score. Journal of the Nepal Medical Association 2018 2018-02-28 /pmc/articles/PMC8997330/ /pubmed/30058634 Text en Journal of the Nepal Medical Association https://creativecommons.org/licenses/by-nc/3.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lama, Susana
Mahato, Shyam Kumar
Chaudhary, Nagendra
Agrawal, Nikhil
Pathak, Santosh
Kurmi, Om Prakash
Bhatia, Baldev
Agarwal, Kailash Nath
Clinico-radiological Observations in Meconium Aspiration Syndrome
title Clinico-radiological Observations in Meconium Aspiration Syndrome
title_full Clinico-radiological Observations in Meconium Aspiration Syndrome
title_fullStr Clinico-radiological Observations in Meconium Aspiration Syndrome
title_full_unstemmed Clinico-radiological Observations in Meconium Aspiration Syndrome
title_short Clinico-radiological Observations in Meconium Aspiration Syndrome
title_sort clinico-radiological observations in meconium aspiration syndrome
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997330/
https://www.ncbi.nlm.nih.gov/pubmed/30058634
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