Chromosome-specific telomere lengths and the minimal functional telomere revealed by nanopore sequencing

We developed a method to tag telomeres and measure telomere length by nanopore sequencing in the yeast S. cerevisiae. Nanopore allows long-read sequencing through the telomere, through the subtelomere, and into unique chromosomal sequence, enabling assignment of telomere length to a specific chromos...

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Detalles Bibliográficos
Autores principales: Sholes, Samantha L., Karimian, Kayarash, Gershman, Ariel, Kelly, Thomas J., Timp, Winston, Greider, Carol W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997346/
https://www.ncbi.nlm.nih.gov/pubmed/34702734
http://dx.doi.org/10.1101/gr.275868.121

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