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Osteogenic Commitment of Human Periodontal Ligament Cells Is Predetermined by Methylation, Chromatin Accessibility and Expression of Key Transcription Factors

Periodontal ligament stem cells (PDLCs) can be used as a valuable source in cell therapies to regenerate bone tissue. However, the potential therapeutic outcomes are unpredictable due to PDLCs’ heterogeneity regarding the capacity for osteoblast differentiation and mineral nodules production. Here,...

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Detalles Bibliográficos
Autores principales:	Assis, Rahyza I. F., Racca, Francesca, Ferreira, Rogério S., Ruiz, Karina G. S., da Silva, Rodrigo A., Clokie, Samuel J. H., Wiench, Malgorzata, Andia, Denise C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997528/ https://www.ncbi.nlm.nih.gov/pubmed/35406691 http://dx.doi.org/10.3390/cells11071126

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