Drosophila as a Model of Unconventional Translation in Spinocerebellar Ataxia Type 3

RNA toxicity contributes to diseases caused by anomalous nucleotide repeat expansions. Recent work demonstrated RNA-based toxicity from repeat-associated, non-AUG-initiated translation (RAN translation). RAN translation occurs around long nucleotide repeats that form hairpin loops, allowing for tran...

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Detalles Bibliográficos
Autores principales: Johnson, Sean L., Prifti, Matthew V., Sujkowski, Alyson, Libohova, Kozeta, Blount, Jessica R., Hong, Luke, Tsou, Wei-Ling, Todi, Sokol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997593/
https://www.ncbi.nlm.nih.gov/pubmed/35406787
http://dx.doi.org/10.3390/cells11071223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997593/
https://www.ncbi.nlm.nih.gov/pubmed/35406787
http://dx.doi.org/10.3390/cells11071223

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