Cargando…

Activation of the Renin–Angiotensin System Disrupts the Cytoskeletal Architecture of Human Urine-Derived Podocytes

High blood pressure is one of the major public health problems that causes severe disorders in several tissues including the human kidney. One of the most important signaling pathways associated with the regulation of blood pressure is the renin–angiotensin system (RAS), with its main mediator angio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Erichsen, Lars, Thimm, Chantelle, Bohndorf, Martina, Rahman, Md Shaifur, Wruck, Wasco, Adjaye, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997628/ https://www.ncbi.nlm.nih.gov/pubmed/35406662 http://dx.doi.org/10.3390/cells11071095

Ejemplares similares

Unveiling Angiotensin II and Losartan-Induced Gene Regulatory Networks Using Human Urine-Derived Podocytes
por: Thimm, Chantelle, et al.
Publicado: (2023)

Derivation of the Immortalized Cell Line UM51-PrePodo-hTERT and Its Responsiveness to Angiotensin II and Activation of the RAAS Pathway
por: Erichsen, Lars, et al.
Publicado: (2023)

The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2(+) Urine Derived Renal Progenitor Cells
por: Rahman, Md Shaifur, et al.
Publicado: (2020)

Secreted Cytokines within the Urine of AKI Patients Modulate TP53 and SIRT1 Levels in a Human Podocyte Cell Model
por: Erichsen, Lars, et al.
Publicado: (2023)

Urine-Based Detection of Biomarkers Indicative of Chronic Kidney Disease in a Patient Cohort from Ghana
por: Wruck, Wasco, et al.
Publicado: (2022)

The presence of human mesenchymal stem cells of renal origin in amniotic fluid increases with gestational time
por: Rahman, Md Shaifur, et al.
Publicado: (2018)

Isolation and Molecular Characterization of Amniotic Fluid-Derived Mesenchymal Stem Cells Obtained from Caesarean Sections
por: Spitzhorn, Lucas-Sebastian, et al.
Publicado: (2017)

IPSC-Derived Neuronal Cultures Carrying the Alzheimer’s Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network
por: Martins, Soraia, et al.
Publicado: (2020)

Human iPSC-derived iMSCs improve bone regeneration in mini-pigs
por: Jungbluth, Pascal, et al.
Publicado: (2019)

The Nephrotoxin Puromycin Aminonucleoside Induces Injury in Kidney Organoids Differentiated from Induced Pluripotent Stem Cells
por: Nguyen, Lisa, et al.
Publicado: (2022)

Correction: Nguyen et al. The Nephrotoxin Puromycin Aminonucleoside Induces Injury in Kidney Organoids Differentiated from Induced Pluripotent Stem Cells. Cells 2022, 11, 635
por: Nguyen, Lisa, et al.
Publicado: (2022)

Human pluripotent stem cell derived HLC transcriptome data enables molecular dissection of hepatogenesis
por: Wruck, Wasco, et al.
Publicado: (2018)

Meta-analysis reveals up-regulation of cholesterol processes in non-alcoholic and down-regulation in alcoholic fatty liver disease
por: Wruck, Wasco, et al.
Publicado: (2017)

Meta-analysis of human prefrontal cortex reveals activation of GFAP and decline of synaptic transmission in the aging brain
por: Wruck, Wasco, et al.
Publicado: (2020)

SARS-CoV-2 receptor ACE2 is co-expressed with genes related to transmembrane serine proteases, viral entry, immunity and cellular stress
por: Wruck, Wasco, et al.
Publicado: (2020)

Detailed phylogenetic analysis tracks transmission of distinct SARS-COV-2 variants from China and Europe to West Africa
por: Wruck, Wasco, et al.
Publicado: (2021)

Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity
por: Calizo, Rhodora C., et al.
Publicado: (2019)

A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference
por: Graffmann, Nina, et al.
Publicado: (2021)

Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature
por: Spitzhorn, Lucas-Sebastian, et al.
Publicado: (2019)

JNK Signalling Regulates Self-Renewal of Proliferative Urine-Derived Renal Progenitor Cells via Inhibition of Ferroptosis
por: Nguyen, Lisa, et al.
Publicado: (2023)

Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II
por: Ma, Yiqiong, et al.
Publicado: (2018)

Transcriptome-based analysis of blood samples reveals elevation of DNA damage response, neutrophil degranulation, cancer and neurodegenerative pathways in Plasmodium falciparum patients
por: Karikari, Akua A., et al.
Publicado: (2021)

Free Bilirubin Induces Neuro-Inflammation in an Induced Pluripotent Stem Cell-Derived Cortical Organoid Model of Crigler-Najjar Syndrome
por: Pranty, Abida Islam, et al.
Publicado: (2023)

miR-27 Negatively Regulates Pluripotency-Associated Genes in Human Embryonal Carcinoma Cells
por: Fuchs, Heiko, et al.
Publicado: (2014)

Cell fate decisions of human iPSC-derived bipotential hepatoblasts depend on cell density
por: Graffmann, Nina, et al.
Publicado: (2018)

Natural Products in Renal-Associated Drug Discovery
por: Wruck, Wasco, et al.
Publicado: (2023)

Human Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Acquire Rejuvenation and Reduced Heterogeneity
por: Wruck, Wasco, et al.
Publicado: (2021)

Gene expression studies of WT1 mutant Wilms tumor cell lines in the frame work of published kidney development data reveals their early kidney stem cell origin
por: Royer-Pokora, Brigitte, et al.
Publicado: (2023)

Angiotensin II Receptor Blocker Attenuates Intrarenal Renin-Angiotensin-System and Podocyte Injury in Rats with Myocardial Infarction
por: Wen, Zhu-zhi, et al.
Publicado: (2013)

Combined sequencing of mRNA and DNA from human embryonic stem cells
por: Mertes, Florian, et al.
Publicado: (2016)

Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidants
por: Mlody, Barbara, et al.
Publicado: (2017)

Methyl Group Metabolism in Differentiation, Aging, and Cancer
por: Erichsen, Lars, et al.
Publicado: (2022)

Footprint-free human fetal foreskin derived iPSCs: A tool for modeling hepatogenesis associated gene regulatory networks
por: Matz, Peggy, et al.
Publicado: (2017)

Crosstalk between age accumulated DNA-damage and the SIRT1-AKT-GSK3ß axis in urine derived renal progenitor cells
por: Erichsen, Lars, et al.
Publicado: (2022)

Impaired p53-Mediated DNA Damage Response Contributes to Microcephaly in Nijmegen Breakage Syndrome Patient-Derived Cerebral Organoids
por: Martins, Soraia, et al.
Publicado: (2022)

Advanced glycation end-products reduce podocyte adhesion by activating the renin-angiotensin system and increasing integrin-linked kinase
por: CHENG, CAILIAN, et al.
Publicado: (2013)

What’s new in the renin-angiotensin system?: What’s new in the renin-angiotensin system?
por: Smith, A. I., et al.
Publicado: (2004)

Renal tubular Bim mediates the tubule-podocyte crosstalk via NFAT2 to induce podocyte cytoskeletal dysfunction
por: Xu, Chunmei, et al.
Publicado: (2020)

Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha
por: Graffmann, Nina, et al.
Publicado: (2016)

The Renin-Angiotensin System Textbook
por: Cumming, Allan D
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_emjmo2qo0d5rglqd4jnjv9cl29