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TRIM72 exerts antitumor effects in breast cancer and modulates lactate production and MCT4 promoter activity by interacting with PPP3CA

A hypoxic tumor microenvironment (TME) promotes cancer progression, yet its value as a therapeutic target remains underexploited. Tripartite motif-containing 72 (TRIM72) may protect cells against various stresses including hypoxia. Recently, low TRIM72 expression has been implicated in cancer progre...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Li, Haixia, Wang, Hongxia, Li, Xin, Zhang, Qiong, Wang, Haifang, Li, Kui, Qiu, Yurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997701/
https://www.ncbi.nlm.nih.gov/pubmed/35324524
http://dx.doi.org/10.1097/CAD.0000000000001304