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TRIM72 exerts antitumor effects in breast cancer and modulates lactate production and MCT4 promoter activity by interacting with PPP3CA
A hypoxic tumor microenvironment (TME) promotes cancer progression, yet its value as a therapeutic target remains underexploited. Tripartite motif-containing 72 (TRIM72) may protect cells against various stresses including hypoxia. Recently, low TRIM72 expression has been implicated in cancer progre...
Autores principales: | Wang, Zheng, Li, Haixia, Wang, Hongxia, Li, Xin, Zhang, Qiong, Wang, Haifang, Li, Kui, Qiu, Yurong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997701/ https://www.ncbi.nlm.nih.gov/pubmed/35324524 http://dx.doi.org/10.1097/CAD.0000000000001304 |
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