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The Seroprevalence of SARS-CoV-2 Antibodies among HealthCare Workers in University Hospital in Krakow before the Era of Vaccination

Background: Knowledge of occupational health is crucial to the safety of healthcare workers in the pandemic period. The aim of our study was the rating of SARS-CoV-2 seroprevalence in connection with selected demographic, social, and organizational factors, as well as the identification of key eleme...

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Autores principales: Żółtowska, Barbara, Barańska, Ilona, Jachowicz, Estera, Sydor, Wojciech, Maziarz, Barbara, Mydel, Krzysztof, Różańska, Anna, Wizner, Barbara, Rosiński, Jerzy, Kossowska, Magdalena, Głomb, Kaja, Wójkowska-Mach, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997762/
https://www.ncbi.nlm.nih.gov/pubmed/35409727
http://dx.doi.org/10.3390/ijerph19074044
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author Żółtowska, Barbara
Barańska, Ilona
Jachowicz, Estera
Sydor, Wojciech
Maziarz, Barbara
Mydel, Krzysztof
Różańska, Anna
Wizner, Barbara
Rosiński, Jerzy
Kossowska, Magdalena
Głomb, Kaja
Wójkowska-Mach, Jadwiga
author_facet Żółtowska, Barbara
Barańska, Ilona
Jachowicz, Estera
Sydor, Wojciech
Maziarz, Barbara
Mydel, Krzysztof
Różańska, Anna
Wizner, Barbara
Rosiński, Jerzy
Kossowska, Magdalena
Głomb, Kaja
Wójkowska-Mach, Jadwiga
author_sort Żółtowska, Barbara
collection PubMed
description Background: Knowledge of occupational health is crucial to the safety of healthcare workers in the pandemic period. The aim of our study was the rating of SARS-CoV-2 seroprevalence in connection with selected demographic, social, and organizational factors, as well as the identification of key elements determining the safety of HCWs and patients of the University Hospital in Krakow. Methods: This was a non-interventional, uncontrolled, open, single-center, cross-sectional online survey on the preparedness for the COVID-19 epidemic and the seroprevalence of medical and non-medical HCWs and students. Serum specimens from 1221 persons were tested using an immunoassay analyzer based on the ECLIA technique for the anti-SARS-CoV-2 antibodies IgM + IgG. Results: The total seroprevalence was 42.7%. In medical students it was 25.2%, while in physicians it was 43.4% and in nurses/midwives it was 48.1%. Of those who tested positive, 21.5% did not know their serological status. The use of personal protective equipment did not have any significant impact on the result of testing for anti-SARS-CoV-2 antibodies. The risk of developing the disease was not influenced by sex, professional work experience, workplace, or intensity of contact with the patient. Among the studied elements, only care of COVID-19 patients significantly increased the risk. The protective factor was starting work between the waves of the epidemic (June–September 2020). Conclusions: PPE is only one element of infection prevention and control—without other components, such as hand hygiene, it can be dangerous and contribute to self-infection. It is also very important to test healthcare workers. Not being aware of the COVID-19 status of HCWs poses a threat to other staff members, as well as patients and the family and friends of the infected. Thus, extreme caution should be applied when employing respirators with exhalation valves during the COVID-19 pandemic.
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spelling pubmed-89977622022-04-12 The Seroprevalence of SARS-CoV-2 Antibodies among HealthCare Workers in University Hospital in Krakow before the Era of Vaccination Żółtowska, Barbara Barańska, Ilona Jachowicz, Estera Sydor, Wojciech Maziarz, Barbara Mydel, Krzysztof Różańska, Anna Wizner, Barbara Rosiński, Jerzy Kossowska, Magdalena Głomb, Kaja Wójkowska-Mach, Jadwiga Int J Environ Res Public Health Article Background: Knowledge of occupational health is crucial to the safety of healthcare workers in the pandemic period. The aim of our study was the rating of SARS-CoV-2 seroprevalence in connection with selected demographic, social, and organizational factors, as well as the identification of key elements determining the safety of HCWs and patients of the University Hospital in Krakow. Methods: This was a non-interventional, uncontrolled, open, single-center, cross-sectional online survey on the preparedness for the COVID-19 epidemic and the seroprevalence of medical and non-medical HCWs and students. Serum specimens from 1221 persons were tested using an immunoassay analyzer based on the ECLIA technique for the anti-SARS-CoV-2 antibodies IgM + IgG. Results: The total seroprevalence was 42.7%. In medical students it was 25.2%, while in physicians it was 43.4% and in nurses/midwives it was 48.1%. Of those who tested positive, 21.5% did not know their serological status. The use of personal protective equipment did not have any significant impact on the result of testing for anti-SARS-CoV-2 antibodies. The risk of developing the disease was not influenced by sex, professional work experience, workplace, or intensity of contact with the patient. Among the studied elements, only care of COVID-19 patients significantly increased the risk. The protective factor was starting work between the waves of the epidemic (June–September 2020). Conclusions: PPE is only one element of infection prevention and control—without other components, such as hand hygiene, it can be dangerous and contribute to self-infection. It is also very important to test healthcare workers. Not being aware of the COVID-19 status of HCWs poses a threat to other staff members, as well as patients and the family and friends of the infected. Thus, extreme caution should be applied when employing respirators with exhalation valves during the COVID-19 pandemic. MDPI 2022-03-29 /pmc/articles/PMC8997762/ /pubmed/35409727 http://dx.doi.org/10.3390/ijerph19074044 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Żółtowska, Barbara
Barańska, Ilona
Jachowicz, Estera
Sydor, Wojciech
Maziarz, Barbara
Mydel, Krzysztof
Różańska, Anna
Wizner, Barbara
Rosiński, Jerzy
Kossowska, Magdalena
Głomb, Kaja
Wójkowska-Mach, Jadwiga
The Seroprevalence of SARS-CoV-2 Antibodies among HealthCare Workers in University Hospital in Krakow before the Era of Vaccination
title The Seroprevalence of SARS-CoV-2 Antibodies among HealthCare Workers in University Hospital in Krakow before the Era of Vaccination
title_full The Seroprevalence of SARS-CoV-2 Antibodies among HealthCare Workers in University Hospital in Krakow before the Era of Vaccination
title_fullStr The Seroprevalence of SARS-CoV-2 Antibodies among HealthCare Workers in University Hospital in Krakow before the Era of Vaccination
title_full_unstemmed The Seroprevalence of SARS-CoV-2 Antibodies among HealthCare Workers in University Hospital in Krakow before the Era of Vaccination
title_short The Seroprevalence of SARS-CoV-2 Antibodies among HealthCare Workers in University Hospital in Krakow before the Era of Vaccination
title_sort seroprevalence of sars-cov-2 antibodies among healthcare workers in university hospital in krakow before the era of vaccination
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997762/
https://www.ncbi.nlm.nih.gov/pubmed/35409727
http://dx.doi.org/10.3390/ijerph19074044
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