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The Non-Linear Path from Gene Dysfunction to Genetic Disease: Lessons from the MICPCH Mouse Model

Most human disease manifests as a result of tissue pathology, due to an underlying disease process (pathogenesis), rather than the acute loss of specific molecular function(s). Successful therapeutic strategies thus may either target the correction of a specific molecular function or halt the diseas...

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Detalles Bibliográficos
Autores principales: Mukherjee, Konark, LaConte, Leslie E. W., Srivastava, Sarika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997851/
https://www.ncbi.nlm.nih.gov/pubmed/35406695
http://dx.doi.org/10.3390/cells11071131