Neutralization of GDF15 Prevents Anorexia and Weight Loss in the Monocrotaline-Induced Cardiac Cachexia Rat Model

Growth and differentiation factor 15 (GDF15) is a cytokine reported to cause anorexia and weight loss in animal models. Neutralization of GDF15 was efficacious in mitigating cachexia and improving survival in cachectic tumor models. Interestingly, elevated circulating GDF15 was reported in patients...

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Detalles Bibliográficos
Autores principales: Albuquerque, Bina, Chen, Xian, Hirenallur-Shanthappa, Dinesh, Zhao, Yang, Stansfield, John C., Zhang, Bei B., Sheikh, Abdul, Wu, Zhidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997866/
https://www.ncbi.nlm.nih.gov/pubmed/35406637
http://dx.doi.org/10.3390/cells11071073

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