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A Novel Role for Plasminogen Activator Inhibitor Type-2 as a Hypochlorite-Resistant Serine Protease Inhibitor and Holdase Chaperone
Plasminogen activator inhibitor type-2 (PAI-2), a member of the serpin family, is dramatically upregulated during pregnancy and in response to inflammation. Although PAI-2 exists in glycosylated and non-glycosylated forms in vivo, the majority of in vitro studies of PAI-2 have exclusively involved t...
Autores principales: | Cater, Jordan H., Mañucat-Tan, Noralyn B., Georgiou, Demi K., Zhao, Guomao, Buhimschi, Irina A., Wyatt, Amy R., Ranson, Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997907/ https://www.ncbi.nlm.nih.gov/pubmed/35406715 http://dx.doi.org/10.3390/cells11071152 |
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