Cargando…

Tissue Microarray Analyses Suggest Axl as a Predictive Biomarker in HPV-Negative Head and Neck Cancer

SIMPLE SUMMARY: Despite many efforts, no predictive biomarkers that could guide clinical decision making and personalized treatment have been established for patients with head and neck squamous cell carcinoma. We propose that high expression of the tyrosine kinase receptor Axl identifies patients a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Busch, Chia-Jung, Hagel, Christian, Becker, Benjamin, Oetting, Agnes, Möckelmann, Nikolaus, Droste, Conrad, Möller-Koop, Christina, Witt, Melanie, Blaurock, Markus, Loges, Sonja, Rothkamm, Kai, Betz, Christian, Münscher, Adrian, Clauditz, Till S., Rieckmann, Thorsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997923/ https://www.ncbi.nlm.nih.gov/pubmed/35406601 http://dx.doi.org/10.3390/cancers14071829

Ejemplares similares

The prognostic impact of B7-H3 and B7-H4 in head and neck squamous cell carcinoma
por: Borgmann, Mara, et al.
Publicado: (2022)

Mass Spectrometric Comparison of HPV-Positive and HPV-Negative Oropharyngeal Cancer
por: Wurlitzer, Marcus, et al.
Publicado: (2020)

Similar cisplatin sensitivity of HPV-positive and -negative HNSCC cell lines
por: Busch, Chia-Jung, et al.
Publicado: (2016)

Dual Inhibition of PARP and the Intra-S/G2 Cell Cycle Checkpoints Results in Highly Effective Radiosensitization of HPV-Positive HNSCC Cells
por: Hintelmann, Katharina, et al.
Publicado: (2021)

DNA Damage Response during Replication Correlates with CIN70 Score and Determines Survival in HNSCC Patients
por: Bold, Ioan T., et al.
Publicado: (2021)

Rational surgical neck management in total laryngectomy for advanced stage laryngeal squamous cell carcinomas
por: Böttcher, Arne, et al.
Publicado: (2020)

Analyzing expression and phosphorylation of the EGF receptor in HNSCC
por: Kriegs, Malte, et al.
Publicado: (2019)

The inflammation-reducing compatible solute ectoine does not impair the cytotoxic effect of ionizing radiation on head and neck cancer cells
por: Rieckmann, Thorsten, et al.
Publicado: (2019)

Outcomes following oropharyngeal squamous cell carcinoma resection and bilateral neck dissection with or without contralateral postoperative radiotherapy of the pathologically node-negative neck
por: Jansen, Florian, et al.
Publicado: (2023)

Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1
por: Oetting, Agnes, et al.
Publicado: (2023)

A Four-Generational Report on Hereditary Head and Neck Paraganglioma
por: Trache, Mihnea Cristian, et al.
Publicado: (2022)

Effect of sorafenib on cisplatin-based chemoradiation in head and neck cancer cells
por: Möckelmann, Nikolaus, et al.
Publicado: (2016)

A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells
por: Köcher, Sabrina, et al.
Publicado: (2022)

IMP3 overexpression occurs in various important cancer types and is linked to aggressive tumor features: A tissue microarray study on 8,877 human cancers and normal tissues
por: Burdelski, Christoph, et al.
Publicado: (2018)

Selectin Binding Sites Are Involved in Cell Adhesive Properties of Head and Neck Squamous Cell Carcinoma
por: Valentiner, Ursula, et al.
Publicado: (2019)

Comparative effectiveness trial of transoral head and neck surgery followed by adjuvant radio(chemo)therapy versus primary radiochemotherapy for oropharyngeal cancer (TopROC)
por: Bußmann, Lara, et al.
Publicado: (2020)

Detection of stage I HPV-driven oropharyngeal cancer in asymptomatic individuals in the Hamburg City Health Study using HPV16 E6 serology – A proof-of-concept study
por: Busch, Chia-Jung, et al.
Publicado: (2022)

Prognostic and diagnostic role of PSA immunohistochemistry: A tissue microarray study on 21,000 normal and cancerous tissues
por: Bonk, Sarah, et al.
Publicado: (2019)

MUC5AC Expression in Various Tumor Types and Nonneoplastic Tissue: A Tissue Microarray Study on 10 399 Tissue Samples
por: Rico, Sebastian Dwertmann, et al.
Publicado: (2021)

Giving AXL the axe: targeting AXL in human malignancy
por: Gay, Carl M, et al.
Publicado: (2017)

Blockade of Axl signaling ameliorates HPV16E6-mediated tumorigenecity of cervical cancer
por: Lee, Eun-Hee, et al.
Publicado: (2017)

Improving the Efficacy of Tumor Radiosensitization Through Combined Molecular Targeting
por: Hintelmann, Katharina, et al.
Publicado: (2020)

AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms
por: Beitzen-Heineke, Antonia, et al.
Publicado: (2021)

Targeting AXL in NSCLC
por: Zaman, Aubhishek, et al.
Publicado: (2021)

Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2
por: Novoyatleva, Tatyana, et al.
Publicado: (2021)

Aktueller Stand zu „liquid biopsy“ und Diagnostik – Beiträge vom ASCO und ESMO 2022
por: Blaurock, Markus, et al.
Publicado: (2023)

The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels
por: Fritz, Helena K., et al.
Publicado: (2015)

Immune Evasion Mechanism and AXL
por: Son, Hye-Youn, et al.
Publicado: (2021)

Patent Spring Washer Axles
Publicado: (1878)

The failure of cetuximab-based de-intensified regimes for HPV-positive OPSCC: A radiobiologists perspective
por: Rieckmann, Thorsten, et al.
Publicado: (2019)

Topology Optimization and Multiobjective Optimization for Drive Axle Housing of a Rear Axle Drive Truck
por: Zheng, Bin, et al.
Publicado: (2022)

MEDB-50. Assessment of cellular radiosensitivity and DNA repair in medulloblastoma cell lines and patient-derivded xenograft slice cultures
por: Feyerabend, Simon, et al.
Publicado: (2022)

Pattern of placental alkaline phosphatase (PLAP) expression in human tumors: a tissue microarray study on 12,381 tumors
por: Reiswich, Viktor, et al.
Publicado: (2021)

E-Cadherin expression in human tumors: a tissue microarray study on 10,851 tumors
por: Burandt, Eike, et al.
Publicado: (2021)

Author Correction: Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2
por: Novoyatleva, Tatyana, et al.
Publicado: (2022)

PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response
por: Wurster, Stephanie, et al.
Publicado: (2016)

Mesothelin Expression in Human Tumors: A Tissue Microarray Study on 12,679 Tumors
por: Weidemann, Sören, et al.
Publicado: (2021)

HPV prevalence and genotype distribution in a population-based split-sample study of well-screened women using CLART HPV2 Human Papillomavirus genotype microarray system
por: Bonde, Jesper, et al.
Publicado: (2014)

Diagnostic and prognostic impact of cytokeratin 18 expression in human tumors: a tissue microarray study on 11,952 tumors
por: Menz, Anne, et al.
Publicado: (2021)

p63 expression in human tumors and normal tissues: a tissue microarray study on 10,200 tumors
por: Steurer, Stefan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8bkpud6kjn5pa5lrnoi990jfkg