Increased Frequency of CD4(+) Follicular Helper T and CD8(+) Follicular T Cells in Human Lymph Node Biopsies during the Earliest Stages of Rheumatoid Arthritis

Follicular T helper cells (Tfh cells) provide key B-cell help and are essential in germinal center formation and (auto) antibody generation. To gain more insight into their role during the earliest phase of rheumatoid arthritis (RA), we analyzed their frequencies, phenotypes, and cytokine profiles i...

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Detalles Bibliográficos
Autores principales: Anang, Dornatien Chuo, Ramwadhdoebe, Tamara H., Hähnlein, Janine S., van Kuijk, Bo, Smits, Noortje, van Lienden, Krijn P., Maas, Mario, Gerlag, Daniëlle M., Tak, Paul P., de Vries, Niek, van Baarsen, Lisa G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997933/
https://www.ncbi.nlm.nih.gov/pubmed/35406668
http://dx.doi.org/10.3390/cells11071104

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