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Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020–2021: Practice Does Not Follow Policy

Inappropriate use of antibiotics during the COVID-19 pandemic has the potential to increase the burden of antimicrobial resistance. In this study, we report on the prevalence of antibiotic use and its associated factors among suspected and confirmed COVID-19 patients admitted to 35 health facilities...

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Autores principales: Kamara, Ibrahim Franklyn, Kumar, Ajay M. V., Maruta, Anna, Fofanah, Bobson Derrick, Njuguna, Charles Kuria, Shongwe, Steven, Moses, Francis, Tengbe, Sia Morenike, Kanu, Joseph Sam, Lakoh, Sulaiman, Mansaray, Alie H. D., Selvaraj, Kalaiselvi, Khogali, Mohammed, Zachariah, Rony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998021/
https://www.ncbi.nlm.nih.gov/pubmed/35409687
http://dx.doi.org/10.3390/ijerph19074005
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author Kamara, Ibrahim Franklyn
Kumar, Ajay M. V.
Maruta, Anna
Fofanah, Bobson Derrick
Njuguna, Charles Kuria
Shongwe, Steven
Moses, Francis
Tengbe, Sia Morenike
Kanu, Joseph Sam
Lakoh, Sulaiman
Mansaray, Alie H. D.
Selvaraj, Kalaiselvi
Khogali, Mohammed
Zachariah, Rony
author_facet Kamara, Ibrahim Franklyn
Kumar, Ajay M. V.
Maruta, Anna
Fofanah, Bobson Derrick
Njuguna, Charles Kuria
Shongwe, Steven
Moses, Francis
Tengbe, Sia Morenike
Kanu, Joseph Sam
Lakoh, Sulaiman
Mansaray, Alie H. D.
Selvaraj, Kalaiselvi
Khogali, Mohammed
Zachariah, Rony
author_sort Kamara, Ibrahim Franklyn
collection PubMed
description Inappropriate use of antibiotics during the COVID-19 pandemic has the potential to increase the burden of antimicrobial resistance. In this study, we report on the prevalence of antibiotic use and its associated factors among suspected and confirmed COVID-19 patients admitted to 35 health facilities in Sierra Leone from March 2020–March 2021. This was a cross-sectional study using routinely collected patient data. Of 700 confirmed COVID-19 patients, 47% received antibiotics. The majority (73%) of the antibiotics belonged to the ’WATCH’ group of antibiotics, which are highly toxic and prone to resistance. The most frequently prescribed antibiotics were azithromycin, ceftriaxone, amoxicillin, metronidazole, and amoxicillin-clavulanic acid. Antibiotic use was significantly higher in patients aged 25–34 years than in those with severe disease. Of 755 suspected COVID-19 patients, 61% received antibiotics, of which the majority (58%) belonged to the ‘WATCH’ category. The most frequently prescribed antibiotics were ceftriaxone, metronidazole, azithromycin, ciprofloxacin, and amoxycillin. The prevalence of antibiotic use among suspected and confirmed COVID-19 patients admitted to healthcare facilities in Sierra Leone was high and not in line with national and WHO case management guidelines. Training of health care providers, strengthening of antimicrobial stewardship programs, and microbiological laboratory capacity are urgently needed.
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spelling pubmed-89980212022-04-12 Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020–2021: Practice Does Not Follow Policy Kamara, Ibrahim Franklyn Kumar, Ajay M. V. Maruta, Anna Fofanah, Bobson Derrick Njuguna, Charles Kuria Shongwe, Steven Moses, Francis Tengbe, Sia Morenike Kanu, Joseph Sam Lakoh, Sulaiman Mansaray, Alie H. D. Selvaraj, Kalaiselvi Khogali, Mohammed Zachariah, Rony Int J Environ Res Public Health Article Inappropriate use of antibiotics during the COVID-19 pandemic has the potential to increase the burden of antimicrobial resistance. In this study, we report on the prevalence of antibiotic use and its associated factors among suspected and confirmed COVID-19 patients admitted to 35 health facilities in Sierra Leone from March 2020–March 2021. This was a cross-sectional study using routinely collected patient data. Of 700 confirmed COVID-19 patients, 47% received antibiotics. The majority (73%) of the antibiotics belonged to the ’WATCH’ group of antibiotics, which are highly toxic and prone to resistance. The most frequently prescribed antibiotics were azithromycin, ceftriaxone, amoxicillin, metronidazole, and amoxicillin-clavulanic acid. Antibiotic use was significantly higher in patients aged 25–34 years than in those with severe disease. Of 755 suspected COVID-19 patients, 61% received antibiotics, of which the majority (58%) belonged to the ‘WATCH’ category. The most frequently prescribed antibiotics were ceftriaxone, metronidazole, azithromycin, ciprofloxacin, and amoxycillin. The prevalence of antibiotic use among suspected and confirmed COVID-19 patients admitted to healthcare facilities in Sierra Leone was high and not in line with national and WHO case management guidelines. Training of health care providers, strengthening of antimicrobial stewardship programs, and microbiological laboratory capacity are urgently needed. MDPI 2022-03-28 /pmc/articles/PMC8998021/ /pubmed/35409687 http://dx.doi.org/10.3390/ijerph19074005 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kamara, Ibrahim Franklyn
Kumar, Ajay M. V.
Maruta, Anna
Fofanah, Bobson Derrick
Njuguna, Charles Kuria
Shongwe, Steven
Moses, Francis
Tengbe, Sia Morenike
Kanu, Joseph Sam
Lakoh, Sulaiman
Mansaray, Alie H. D.
Selvaraj, Kalaiselvi
Khogali, Mohammed
Zachariah, Rony
Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020–2021: Practice Does Not Follow Policy
title Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020–2021: Practice Does Not Follow Policy
title_full Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020–2021: Practice Does Not Follow Policy
title_fullStr Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020–2021: Practice Does Not Follow Policy
title_full_unstemmed Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020–2021: Practice Does Not Follow Policy
title_short Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020–2021: Practice Does Not Follow Policy
title_sort antibiotic use in suspected and confirmed covid-19 patients admitted to health facilities in sierra leone in 2020–2021: practice does not follow policy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998021/
https://www.ncbi.nlm.nih.gov/pubmed/35409687
http://dx.doi.org/10.3390/ijerph19074005
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