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TGF-β1 Reduces Neutrophil Adhesion and Prevents Acute Vaso-Occlusive Processes in Sickle Cell Disease Mice

Sickle cell disease (SCD) patients experience chronic inflammation and recurrent vaso-occlusive episodes during their entire lifetime. Inflammation in SCD occurs with the overexpression of several inflammatory mediators, including transforming growth factor beta-1 (TGF-β1), a major immune regulator....

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Detalles Bibliográficos
Autores principales: Torres, Lidiane S., Chweih, Hanan, Fabris, Fernanda C. Z., Gotardo, Erica M. F., Leonardo, Flávia C., Saad, Sara T. Olalla, Costa, Fernando F., Conran, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998040/
https://www.ncbi.nlm.nih.gov/pubmed/35406764
http://dx.doi.org/10.3390/cells11071200

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