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TGF-β1 Reduces Neutrophil Adhesion and Prevents Acute Vaso-Occlusive Processes in Sickle Cell Disease Mice
Sickle cell disease (SCD) patients experience chronic inflammation and recurrent vaso-occlusive episodes during their entire lifetime. Inflammation in SCD occurs with the overexpression of several inflammatory mediators, including transforming growth factor beta-1 (TGF-β1), a major immune regulator....
Autores principales: | Torres, Lidiane S., Chweih, Hanan, Fabris, Fernanda C. Z., Gotardo, Erica M. F., Leonardo, Flávia C., Saad, Sara T. Olalla, Costa, Fernando F., Conran, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998040/ https://www.ncbi.nlm.nih.gov/pubmed/35406764 http://dx.doi.org/10.3390/cells11071200 |
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