Lysophosphatidic Acid Receptor 5 (LPA(5)) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In Vitro

Systemic inflammation induces alterations in the finely tuned micromilieu of the brain that is continuously monitored by microglia. In the CNS, these changes include increased synthesis of the bioactive lipid lysophosphatidic acid (LPA), a ligand for the six members of the LPA receptor family (LPA(1...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Lisha, Plastira, Ioanna, Bernhart, Eva, Reicher, Helga, Koshenov, Zhanat, Graier, Wolfgang F., Vujic, Nemanja, Kratky, Dagmar, Rivera, Richard, Chun, Jerold, Sattler, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998093/
https://www.ncbi.nlm.nih.gov/pubmed/35406635
http://dx.doi.org/10.3390/cells11071071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998093/
https://www.ncbi.nlm.nih.gov/pubmed/35406635
http://dx.doi.org/10.3390/cells11071071

Ejemplares similares