CFTR Modulator Therapies: Potential Impact on Airway Infections in Cystic Fibrosis

Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding for the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein, expressed on the apical surface of epithelial cells. CFTR absence/dysfunction results in ion imbalance and airway surface dehydr...

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Detalles Bibliográficos
Autores principales: Saluzzo, Francesca, Riberi, Luca, Messore, Barbara, Loré, Nicola Ivan, Esposito, Irene, Bignamini, Elisabetta, De Rose, Virginia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998122/
https://www.ncbi.nlm.nih.gov/pubmed/35406809
http://dx.doi.org/10.3390/cells11071243

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