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Therapeutic Potential of Combining IL-6 and TNF Blockade in a Mouse Model of Allergic Asthma

Combined anti-cytokine therapy is a promising therapeutic approach for uncontrolled steroid-resistant asthma. In this regard, simultaneous blockade of IL-4 and IL-13 signaling by Dupilumab (anti-IL-4Ra monoclonal antibody) was recently approved for severe eosinophilic asthma. However, no therapeutic...

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Detalles Bibliográficos
Autores principales:	Namakanova, Olga A., Gorshkova, Ekaterina A., Zvartsev, Ruslan V., Nedospasov, Sergei A., Drutskaya, Marina S., Gubernatorova, Ekaterina O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998171/ https://www.ncbi.nlm.nih.gov/pubmed/35408882 http://dx.doi.org/10.3390/ijms23073521

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