Metabolic Alterations in Cellular Senescence: The Role of Citrate in Ageing and Age-Related Disease

Recent mouse model experiments support an instrumental role for senescent cells in age-related diseases and senescent cells may be causal to certain age-related pathologies. A strongly supported hypothesis is that extranuclear chromatin is recognized by the cyclic GMP–AMP synthase-stimulator of inte...

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Detalles Bibliográficos
Autores principales: Mycielska, Maria Elzbieta, James, Emma Naomi, Parkinson, Eric Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998297/
https://www.ncbi.nlm.nih.gov/pubmed/35409012
http://dx.doi.org/10.3390/ijms23073652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998297/
https://www.ncbi.nlm.nih.gov/pubmed/35409012
http://dx.doi.org/10.3390/ijms23073652

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