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Metabolic Alterations in Cellular Senescence: The Role of Citrate in Ageing and Age-Related Disease
Recent mouse model experiments support an instrumental role for senescent cells in age-related diseases and senescent cells may be causal to certain age-related pathologies. A strongly supported hypothesis is that extranuclear chromatin is recognized by the cyclic GMP–AMP synthase-stimulator of inte...
Autores principales: | Mycielska, Maria Elzbieta, James, Emma Naomi, Parkinson, Eric Kenneth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998297/ https://www.ncbi.nlm.nih.gov/pubmed/35409012 http://dx.doi.org/10.3390/ijms23073652 |
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