Cargando…

7-Ketocholesterol-Induced Micro-RNA-107-5p Increases Number and Activity of Osteoclasts by Targeting MKP1

Osteoclasts (OCs), which are responsible for bone resorption, play a critical role in cholesterol-induced bone loss and recent studies have suggested that various micro-RNAs (miRs) contribute to modulating OCs. We hypothesized that 7-ketocholesterol (7-KC), a metabolite responsible for cholesterol-i...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Guoen, Sul, Ok-Joo, Yu, Rina, Choi, Hye-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998300/
https://www.ncbi.nlm.nih.gov/pubmed/35409056
http://dx.doi.org/10.3390/ijms23073697