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New Insights into Hemopexin-Binding to Hemin and Hemoglobin
Hemopexin (Hx) is a plasma glycoprotein that scavenges heme (Fe(III) protoporphyrin IX). Hx has important implications in hemolytic disorders and hemorrhagic conditions because releasing hemoglobin increases the labile heme, which is potentially toxic, thus producing oxidative stress. Therefore, Hx...
Autores principales: | Lechuga, Guilherme C., Napoleão-Pêgo, Paloma, Morel, Carlos M., Provance, David W., De-Simone, Salvatore G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998376/ https://www.ncbi.nlm.nih.gov/pubmed/35409149 http://dx.doi.org/10.3390/ijms23073789 |
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