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Optimization of Short RNA Aptamers for TNBC Cell Targeting

Triple-negative breast cancer (TNBC) is an aggressive cancer with limited targeted therapies. RNA aptamers, suitably chemically modified, work for therapeutic purposes in the same way as antibodies. We recently generated 2′Fluoro-pyrimidines RNA-aptamers that act as effective recognition elements fo...

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Detalles Bibliográficos
Autores principales: Camorani, Simona, d’Argenio, Annachiara, Agnello, Lisa, Nilo, Roberto, Zannetti, Antonella, Ibarra, Luis Exequiel, Fedele, Monica, Cerchia, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998535/
https://www.ncbi.nlm.nih.gov/pubmed/35408872
http://dx.doi.org/10.3390/ijms23073511

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