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Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone

Surgical site infections (SSIs) are common postoperative complications. Surgical antibiotic prophylaxis (SAP) can prevent the occurrence of SSIs if administered appropriately. We carried out a retrospective cohort study to determine the incidence of SSIs and assess whether SAP were administered acco...

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Autores principales: Carshon-Marsh, Ronald, Squire, James Sylvester, Kamara, Kadijatu Nabbie, Sargsyan, Aelita, Delamou, Alexandre, Camara, Bienvenu Salim, Manzi, Marcel, Guth, Jamie Ann, Khogali, Mohamed Ahmed, Reid, Anthony, Kenneh, Sartie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998544/
https://www.ncbi.nlm.nih.gov/pubmed/35409731
http://dx.doi.org/10.3390/ijerph19074048
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author Carshon-Marsh, Ronald
Squire, James Sylvester
Kamara, Kadijatu Nabbie
Sargsyan, Aelita
Delamou, Alexandre
Camara, Bienvenu Salim
Manzi, Marcel
Guth, Jamie Ann
Khogali, Mohamed Ahmed
Reid, Anthony
Kenneh, Sartie
author_facet Carshon-Marsh, Ronald
Squire, James Sylvester
Kamara, Kadijatu Nabbie
Sargsyan, Aelita
Delamou, Alexandre
Camara, Bienvenu Salim
Manzi, Marcel
Guth, Jamie Ann
Khogali, Mohamed Ahmed
Reid, Anthony
Kenneh, Sartie
author_sort Carshon-Marsh, Ronald
collection PubMed
description Surgical site infections (SSIs) are common postoperative complications. Surgical antibiotic prophylaxis (SAP) can prevent the occurrence of SSIs if administered appropriately. We carried out a retrospective cohort study to determine the incidence of SSIs and assess whether SAP were administered according to WHO guidelines for Caesarean section (CS) and herniorrhaphy patients in Bo regional government hospital from November 2019 to October 2020. The analysis included 681 patients (599 CSs and 82 herniorrhaphies). Overall, the SSI rate was 6.7% among all patients, and 7.5% and 1.2% among CS patients and herniorrhaphy patients, respectively. SAP was administered preoperatively in 85% of CS and 70% of herniorrhaphy patients. Postoperative antibiotics were prescribed to 85% of CS and 100% of herniorrhaphy patients. Ampicillin, metronidazole, and amoxicillin were the most commonly used antibiotics. The relatively low rate of SSIs observed in this study is probably due to improved infection prevention and control (IPC) measures following the Ebola outbreak and the current COVID-19 pandemic. A good compliance rate with WHO guidelines for preoperative SAP was observed. However, there was a high use of postoperative antibiotics, which is not in line with WHO guidelines. Recommendations were made to ensure the appropriate administration of SAP and reduce unnecessary use of antibiotics.
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spelling pubmed-89985442022-04-12 Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone Carshon-Marsh, Ronald Squire, James Sylvester Kamara, Kadijatu Nabbie Sargsyan, Aelita Delamou, Alexandre Camara, Bienvenu Salim Manzi, Marcel Guth, Jamie Ann Khogali, Mohamed Ahmed Reid, Anthony Kenneh, Sartie Int J Environ Res Public Health Article Surgical site infections (SSIs) are common postoperative complications. Surgical antibiotic prophylaxis (SAP) can prevent the occurrence of SSIs if administered appropriately. We carried out a retrospective cohort study to determine the incidence of SSIs and assess whether SAP were administered according to WHO guidelines for Caesarean section (CS) and herniorrhaphy patients in Bo regional government hospital from November 2019 to October 2020. The analysis included 681 patients (599 CSs and 82 herniorrhaphies). Overall, the SSI rate was 6.7% among all patients, and 7.5% and 1.2% among CS patients and herniorrhaphy patients, respectively. SAP was administered preoperatively in 85% of CS and 70% of herniorrhaphy patients. Postoperative antibiotics were prescribed to 85% of CS and 100% of herniorrhaphy patients. Ampicillin, metronidazole, and amoxicillin were the most commonly used antibiotics. The relatively low rate of SSIs observed in this study is probably due to improved infection prevention and control (IPC) measures following the Ebola outbreak and the current COVID-19 pandemic. A good compliance rate with WHO guidelines for preoperative SAP was observed. However, there was a high use of postoperative antibiotics, which is not in line with WHO guidelines. Recommendations were made to ensure the appropriate administration of SAP and reduce unnecessary use of antibiotics. MDPI 2022-03-29 /pmc/articles/PMC8998544/ /pubmed/35409731 http://dx.doi.org/10.3390/ijerph19074048 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Carshon-Marsh, Ronald
Squire, James Sylvester
Kamara, Kadijatu Nabbie
Sargsyan, Aelita
Delamou, Alexandre
Camara, Bienvenu Salim
Manzi, Marcel
Guth, Jamie Ann
Khogali, Mohamed Ahmed
Reid, Anthony
Kenneh, Sartie
Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone
title Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone
title_full Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone
title_fullStr Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone
title_full_unstemmed Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone
title_short Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone
title_sort incidence of surgical site infection and use of antibiotics among patients who underwent caesarean section and herniorrhaphy at a regional referral hospital, sierra leone
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998544/
https://www.ncbi.nlm.nih.gov/pubmed/35409731
http://dx.doi.org/10.3390/ijerph19074048
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