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Potential Resistance of SARS-CoV-2 Main Protease (Mpro) against Protease Inhibitors: Lessons Learned from HIV-1 Protease

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome 2 (SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of potent novel antivirals had led to global health crises; however, emergence and approval of potent inhibitors of the viral...

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Detalles Bibliográficos
Autores principales: Mótyán, János András, Mahdi, Mohamed, Hoffka, Gyula, Tőzsér, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998604/
https://www.ncbi.nlm.nih.gov/pubmed/35408866
http://dx.doi.org/10.3390/ijms23073507

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