Skin Microbiota in Atopic Dermatitis

The skin microbiota represents an ecosystem composed of numerous microbial species interacting with each other, as well as with host epithelial and immune cells. The microbiota provides health benefits to the host by supporting essential functions of the skin and inhibiting colonization with pathoge...

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Autores principales: Hrestak, Dora, Matijašić, Mario, Čipčić Paljetak, Hana, Ledić Drvar, Daniela, Ljubojević Hadžavdić, Suzana, Perić, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998607/
https://www.ncbi.nlm.nih.gov/pubmed/35408862
http://dx.doi.org/10.3390/ijms23073503
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author Hrestak, Dora
Matijašić, Mario
Čipčić Paljetak, Hana
Ledić Drvar, Daniela
Ljubojević Hadžavdić, Suzana
Perić, Mihaela
author_facet Hrestak, Dora
Matijašić, Mario
Čipčić Paljetak, Hana
Ledić Drvar, Daniela
Ljubojević Hadžavdić, Suzana
Perić, Mihaela
author_sort Hrestak, Dora
collection PubMed
description The skin microbiota represents an ecosystem composed of numerous microbial species interacting with each other, as well as with host epithelial and immune cells. The microbiota provides health benefits to the host by supporting essential functions of the skin and inhibiting colonization with pathogens. However, the disturbance of the microbial balance can result in dysbiosis and promote skin diseases, such as atopic dermatitis (AD). This review provides a current overview of the skin microbiota involvement in AD and its complex interplay with host immune response mechanisms, as well as novel therapeutic strategies for treating AD focused on restoring skin microbial homeostasis.
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spelling pubmed-89986072022-04-12 Skin Microbiota in Atopic Dermatitis Hrestak, Dora Matijašić, Mario Čipčić Paljetak, Hana Ledić Drvar, Daniela Ljubojević Hadžavdić, Suzana Perić, Mihaela Int J Mol Sci Review The skin microbiota represents an ecosystem composed of numerous microbial species interacting with each other, as well as with host epithelial and immune cells. The microbiota provides health benefits to the host by supporting essential functions of the skin and inhibiting colonization with pathogens. However, the disturbance of the microbial balance can result in dysbiosis and promote skin diseases, such as atopic dermatitis (AD). This review provides a current overview of the skin microbiota involvement in AD and its complex interplay with host immune response mechanisms, as well as novel therapeutic strategies for treating AD focused on restoring skin microbial homeostasis. MDPI 2022-03-23 /pmc/articles/PMC8998607/ /pubmed/35408862 http://dx.doi.org/10.3390/ijms23073503 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hrestak, Dora
Matijašić, Mario
Čipčić Paljetak, Hana
Ledić Drvar, Daniela
Ljubojević Hadžavdić, Suzana
Perić, Mihaela
Skin Microbiota in Atopic Dermatitis
title Skin Microbiota in Atopic Dermatitis
title_full Skin Microbiota in Atopic Dermatitis
title_fullStr Skin Microbiota in Atopic Dermatitis
title_full_unstemmed Skin Microbiota in Atopic Dermatitis
title_short Skin Microbiota in Atopic Dermatitis
title_sort skin microbiota in atopic dermatitis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998607/
https://www.ncbi.nlm.nih.gov/pubmed/35408862
http://dx.doi.org/10.3390/ijms23073503
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AT ledicdrvardaniela skinmicrobiotainatopicdermatitis
AT ljubojevichadzavdicsuzana skinmicrobiotainatopicdermatitis
AT pericmihaela skinmicrobiotainatopicdermatitis

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