Identification of Novel GSK-3β Hits Using Competitive Biophysical Assays

Glycogen synthase kinase 3 beta (GSK-3β) is an evolutionarily conserved serine-threonine kinase dysregulated in numerous pathologies, such as Alzheimer’s disease and cancer. Even though GSK-3β is a validated pharmacological target most of its inhibitors have two main limitations: the lack of selecti...

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Detalles Bibliográficos
Autores principales: Balboni, Beatrice, Tripathi, Shailesh Kumar, Veronesi, Marina, Russo, Debora, Penna, Ilaria, Giabbai, Barbara, Bandiera, Tiziano, Storici, Paola, Girotto, Stefania, Cavalli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998611/
https://www.ncbi.nlm.nih.gov/pubmed/35409221
http://dx.doi.org/10.3390/ijms23073856

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