Induction by Phenobarbital of Phase I and II Xenobiotic-Metabolizing Enzymes in Bovine Liver: An Overall Catalytic and Immunochemical Characterization

In cattle, phenobarbital (PB) upregulates target drug-metabolizing enzyme (DME) mRNA levels. However, few data about PB’s post-transcriptional effects are actually available. This work provides the first, and an almost complete, characterization of PB-dependent changes in DME catalytic activities in...

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Detalles Bibliográficos
Autores principales: Cantiello, Michela, Carletti, Monica, Giantin, Mery, Gardini, Giulia, Capolongo, Francesca, Cascio, Paolo, Pauletto, Marianna, Girolami, Flavia, Dacasto, Mauro, Nebbia, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998613/
https://www.ncbi.nlm.nih.gov/pubmed/35408925
http://dx.doi.org/10.3390/ijms23073564

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