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Bromodomain Inhibitor JQ1 Provides Novel Insights and Perspectives in Rhabdomyosarcoma Treatment

Rhabdomyosarcoma (RMS) is the most common type of pediatric soft tissue sarcoma. It is classified into two main subtypes: embryonal (eRMS) and alveolar (aRMS). MYC family proteins are frequently highly expressed in RMS tumors, with the highest levels correlated with poor prognosis. A pharmacological...

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Detalles Bibliográficos
Autores principales: Marchesi, Irene, Fais, Milena, Fiorentino, Francesco Paolo, Bordoni, Valentina, Sanna, Luca, Zoroddu, Stefano, Bagella, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998669/
https://www.ncbi.nlm.nih.gov/pubmed/35408939
http://dx.doi.org/10.3390/ijms23073581