Tolerogenic IDO1(+)CD83(−) Langerhans Cells in Sentinel Lymph Nodes of Patients with Melanoma

Langerhans cells (LCs) are crucial regulators of anti-cancer immune responses. Cancer, however, can alter DCs functions leading to tolerance. The enzyme indoleamine 2,3-dioxygenase (IDO1) plays a crucial role in this process. In sentinel lymph nodes (SLNs) of patients with melanoma, LCs show phenoty...

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Detalles Bibliográficos
Autores principales: Gerlini, Gianni, Di Gennaro, Paola, Pimpinelli, Nicola, Sestini, Serena, Borgognoni, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998685/
https://www.ncbi.nlm.nih.gov/pubmed/35408802
http://dx.doi.org/10.3390/ijms23073441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998685/
https://www.ncbi.nlm.nih.gov/pubmed/35408802
http://dx.doi.org/10.3390/ijms23073441

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