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Tolerogenic IDO1(+)CD83(−) Langerhans Cells in Sentinel Lymph Nodes of Patients with Melanoma
Langerhans cells (LCs) are crucial regulators of anti-cancer immune responses. Cancer, however, can alter DCs functions leading to tolerance. The enzyme indoleamine 2,3-dioxygenase (IDO1) plays a crucial role in this process. In sentinel lymph nodes (SLNs) of patients with melanoma, LCs show phenoty...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998685/ https://www.ncbi.nlm.nih.gov/pubmed/35408802 http://dx.doi.org/10.3390/ijms23073441 |