Cargando…

MicroRNAs Expression in Response to rhNGF in Epithelial Corneal Cells: Focus on Neurotrophin Signaling Pathway

Purpose. Nerve growth factor efficacy was demonstrated for corneal lesions treatment, and recombinant human NGF (rhNGF) was approved for neurotrophic keratitis therapy. However, NGF-induced molecular responses in cornea are still largely unknown. We analyzed microRNAs expression in human epithelial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Compagnoni, Chiara, Zelli, Veronica, Bianchi, Andrea, Di Marco, Antinisca, Capelli, Roberta, Vecchiotti, Davide, Brandolini, Laura, Cimini, Anna Maria, Zazzeroni, Francesca, Allegretti, Marcello, Alesse, Edoardo, Tessitore, Alessandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998691/ https://www.ncbi.nlm.nih.gov/pubmed/35408969 http://dx.doi.org/10.3390/ijms23073597

Ejemplares similares

Intravitreal Administration of rhNGF Enhances Regenerative Processes in a Zebrafish Model of Retinal Degeneration
por: Cocchiaro, Pasquale, et al.
Publicado: (2022)

Adsorption of the rhNGF Protein on Polypropylene with Different Grades of Copolymerization
por: Canepa, Paolo, et al.
Publicado: (2023)

Intranasal delivery of NGF rescues hearing impairment in aged SAMP8 mice
por: Castelli, Vanessa, et al.
Publicado: (2023)

Emerging Role of isomiRs in Cancer: State of the Art and Recent Advances
por: Zelli, Veronica, et al.
Publicado: (2021)

MiR-182-5p Is Upregulated in Hepatic Tissues from a Diet-Induced NAFLD/NASH/HCC C57BL/6J Mouse Model and Modulates Cyld and Foxo1 Expression
por: Compagnoni, Chiara, et al.
Publicado: (2023)

Role of exosomal microRNAs in cancer therapy and drug resistance mechanisms: focus on hepatocellular carcinoma
por: Zelli, Veronica, et al.
Publicado: (2022)

Circulating MicroRNAs as Prognostic and Therapeutic Biomarkers in Breast Cancer Molecular Subtypes
por: Zelli, Veronica, et al.
Publicado: (2020)

Applications of Next Generation Sequencing to the Analysis of Familial Breast/Ovarian Cancer
por: Zelli, Veronica, et al.
Publicado: (2020)

Classification of tumor types using XGBoost machine learning model: a vector space transformation of genomic alterations
por: Zelli, Veronica, et al.
Publicado: (2023)

Next-generation sequencing: recent applications to the analysis of colorectal cancer
por: Del Vecchio, Filippo, et al.
Publicado: (2017)

Concurrent RAS and RAS/BRAF V600E Variants in Colorectal Cancer: More Frequent Than Expected? A Case Report
por: Zelli, Veronica, et al.
Publicado: (2022)

Effective regeneration of rat sciatic nerve using nanofibrous scaffolds containing rat ADSCs with controlled release of rhNGF and melatonin molecules for the treatment of peripheral injury model
por: Zhang, Jincheng, et al.
Publicado: (2023)

Bioinformatics approach to predict target genes for dysregulated microRNAs in hepatocellular carcinoma: study on a chemically-induced HCC mouse model
por: Del Vecchio, Filippo, et al.
Publicado: (2015)

Ultrasound-Based Method for the Identification of Novel MicroRNA Biomarkers in Prostate Cancer
por: Cornice, Jessica, et al.
Publicado: (2021)

MicroRNAs in the DNA Damage/Repair Network and Cancer
por: Tessitore, Alessandra, et al.
Publicado: (2014)

KCTD11 Tumor Suppressor Gene Expression Is Reduced in Prostate Adenocarcinoma
por: Zazzeroni, Francesca, et al.
Publicado: (2014)

Life, death, and autophagy in cancer: NF-κB turns up everywhere
por: Verzella, Daniela, et al.
Publicado: (2020)

Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions
por: Paoletti, Francesca, et al.
Publicado: (2021)

EV-Mediated Chemoresistance in the Tumor Microenvironment: Is NF-κB a Player?
por: Di Vito Nolfi, Mauro, et al.
Publicado: (2022)

Molecular Mechanisms Underpinning Immunometabolic Reprogramming: How the Wind Changes during Cancer Progression
por: Flati, Irene, et al.
Publicado: (2023)

Serum Biomarkers Identification by Mass Spectrometry in High-Mortality Tumors
por: Tessitore, Alessandra, et al.
Publicado: (2013)

The Inflammatory Microenvironment in Hepatocellular Carcinoma: A Pivotal Role for Tumor-Associated Macrophages
por: Capece, Daria, et al.
Publicado: (2013)

Chemokine Signaling in Chemotherapy-Induced Neuropathic Pain
por: Brandolini, Laura, et al.
Publicado: (2019)

Low Radiation Environment Switches the Overgrowth-Induced Cell Apoptosis Toward Autophagy
por: Fischietti, Mariafausta, et al.
Publicado: (2021)

Mitotic phosphorylation of Tau/MAPT modulates cell cycle progression in prostate cancer cells
por: Clementi, Letizia, et al.
Publicado: (2023)

NGF and NGF-receptor expression of cultured immortalized human corneal endothelial cells
por: Sornelli, Federica, et al.
Publicado: (2010)

Elevated NF-κB/SHh/GLI1 Signature Denotes a Worse Prognosis and Represent a Novel Potential Therapeutic Target in Advanced Prostate Cancer
por: Vecchiotti, Davide, et al.
Publicado: (2022)

NGF and Neurotrophin-3 Both Activate TrkA on Sympathetic Neurons but Differentially Regulate Survival and Neuritogenesis
por: Belliveau, Daniel J., et al.
Publicado: (1997)

NF-κB: A Druggable Target in Acute Myeloid Leukemia
por: Di Francesco, Barbara, et al.
Publicado: (2022)

Targeting Costimulatory Molecules to Improve Antitumor Immunity
por: Capece, Daria, et al.
Publicado: (2012)

Targeting Neurotrophins to Specific Populations of Neurons: NGF, BDNF, and NT-3 and Their Relevance for Treatment of Spinal Cord Injury
por: Keefe, Kathleen M., et al.
Publicado: (2017)

Development of hepatocellular cancer induced by long term low fat-high carbohydrate diet in a NAFLD/NASH mouse model
por: Tessitore, Alessandra, et al.
Publicado: (2017)

Mesenchymal stem cells of Systemic Sclerosis patients, derived from different sources, show a profibrotic microRNA profiling
por: Di Benedetto, Paola, et al.
Publicado: (2019)

Neurotrophic Keratopathy in Systemic Diseases: A Case Series on Patients Treated With rh-NGF
por: Meduri, Alessandro, et al.
Publicado: (2022)

NSAIDs-dependent adaption of the mitochondria-proteasome system in immortalized human cardiomyocytes
por: Brandolini, Laura, et al.
Publicado: (2020)

Taurine and oxidative stress in retinal health and disease
por: Castelli, Vanessa, et al.
Publicado: (2021)

CXCR1/2 Inhibitor Ladarixin Ameliorates the Insulin Resistance of 3T3-L1 Adipocytes by Inhibiting Inflammation and Improving Insulin Signaling
por: Castelli, Vanessa, et al.
Publicado: (2021)

MicroRNA expression analysis in high fat diet-induced NAFLD-NASH-HCC progression: study on C57BL/6J mice
por: Tessitore, Alessandra, et al.
Publicado: (2016)

Anthracycline-Free Neoadjuvant Treatment in Patients with HER2-Positive Breast Cancer: Real-Life Use of Pertuzumab, Trastuzumab and Taxanes Association with an Exploratory Analysis of PIK3CA Mutational Status
por: Irelli, Azzurra, et al.
Publicado: (2022)

Autocrine CXCL8-dependent invasiveness triggers modulation of actin cytoskeletal network and cell dynamics
por: Antonosante, Andrea, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8dbogtf6joa22uug0q4bj5auqf