Sirt3 Pharmacologically Promotes Insulin Sensitivity through PI3/AKT/mTOR and Their Downstream Pathway in Adipocytes

Sirtuin-3 (Sirt3) is a major mitochondrial deacetylase enzyme that regulates multiple metabolic pathways, and its expression is decreased in diabetes type 1 and type 2 diabetes. This study aimed to elucidate Sirt3′s molecular mechanism in regulating insulin sensitivity in adipocytes that can contrib...

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Detalles Bibliográficos
Autores principales: Lee, Alexandra Yatine, Christensen, Sabrina Marie, Duong, Nhi, Tran, Quoc-Anh, Xiong, Hou Mai, Huang, Jennifer, James, Sarah, Vallabh, Dimple, Talbott, George, Rose, Melanie, Ho, Linh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998733/
https://www.ncbi.nlm.nih.gov/pubmed/35409099
http://dx.doi.org/10.3390/ijms23073740

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