Cargando…

The Involvement of the Endogenous Opioid System in the Gastrointestinal Aging in Mice and Humans

Nearly 20% of elderly patients suffer from constipation, but the age-related changes in the gastrointestinal (GI) tract remain insufficiently elucidated. In this study, the alterations within the endogenous opioid system (EOS) as a potential cause of constipation in the elderly were evaluated. The G...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szymaszkiewicz, Agata, Talar, Marcin, Włodarczyk, Jakub, Świerczyński, Mikołaj, Bartoszek, Adrian, Krajewska, Julia, Mokrowiecka, Anna, Małecka-Wojciesko, Ewa, Fichna, Jakub, Zielińska, Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998735/ https://www.ncbi.nlm.nih.gov/pubmed/35408926 http://dx.doi.org/10.3390/ijms23073565

Ejemplares similares

Critical interactions between opioid and cannabinoid receptors during tolerance and physical dependence development to opioids in the murine gastrointestinal tract: proof of concept
por: Szymaszkiewicz, Agata, et al.
Publicado: (2021)

Protease-Activated Receptors – Key Regulators of Inflammatory Bowel Diseases Progression
por: Jacenik, Damian, et al.
Publicado: (2021)

Characterization of the Synergistic Effect between Ligands of Opioid and Free Fatty Acid Receptors in the Mouse Model of Colitis
por: Binienda, Agata, et al.
Publicado: (2021)

Serum Levels of Chemerin in Patients with Inflammatory Bowel Disease as an Indicator of Anti-TNF Treatment Efficacy
por: Sochal, Marcin, et al.
Publicado: (2021)

Desensitization of transient receptor potential vanilloid type-1 (TRPV1) channel as promising therapy of irritable bowel syndrome: characterization of the action of palvanil in the mouse gastrointestinal tract
por: Szymaszkiewicz, Agata, et al.
Publicado: (2020)

Expression of FFAR3 and FFAR4 Is Increased in Gastroesophageal Reflux Disease
por: Fabisiak, Adam, et al.
Publicado: (2020)

Relation between Selected Sleep Parameters, Depression, Anti-Tumor Necrosis Factor Therapy, and the Brain-Derived Neurotrophic Factor Pathway in Inflammatory Bowel Disease
por: Sochal, Marcin, et al.
Publicado: (2023)

The Effect of Serotonin Transmission on Depressive and Insomnia Symptoms in Inflammatory Bowel Diseases
por: Sochal, Marcin, et al.
Publicado: (2023)

G protein-coupled estrogen receptor mediates anti-inflammatory action in Crohn’s disease
por: Jacenik, Damian, et al.
Publicado: (2019)

Colonic inflammation induces changes in glucose levels through modulation of incretin system
por: Zatorski, Hubert, et al.
Publicado: (2021)

Sex- and Age-Related Estrogen Signaling Alteration in Inflammatory Bowel Diseases: Modulatory Role of Estrogen Receptors
por: Jacenik, Damian, et al.
Publicado: (2019)

The Anti-Inflammatory Effect of Acidic Mammalian Chitinase Inhibitor OAT-177 in DSS-Induced Mouse Model of Colitis
por: Mazur, Marzena, et al.
Publicado: (2022)

CA 19-9 but Not IGF-1/IGFBP-2 Is a Useful Biomarker for Pancreatic Ductal Adenocarcinoma (PDAC) and Chronic Pancreatitis (CP) Differentiation
por: Wlodarczyk, Barbara, et al.
Publicado: (2023)

Opioids in Cancer Development, Progression and Metastasis: Focus on Colorectal Cancer
por: Szczepaniak, Adrian, et al.
Publicado: (2020)

Risk Stratification of Endoscopic Submucosal Dissection in Colon Tumors
por: Winter, Katarzyna, et al.
Publicado: (2022)

Activation of Free Fatty Acid Receptor 4 Affects Intestinal Inflammation and Improves Colon Permeability in Mice
por: Salaga, Maciej, et al.
Publicado: (2021)

Blockade of fructose transporter protein GLUT5 inhibits proliferation of colon cancer cells: proof of concept for a new class of anti-tumor therapeutics
por: Włodarczyk, Jakub, et al.
Publicado: (2021)

Focus on current and future management possibilities in inflammatory bowel disease-related chronic pain
por: Zielińska, Anna, et al.
Publicado: (2018)

The association of the quality of sleep with proinflammatory cytokine profile in inflammatory bowel disease patients
por: Sobolewska-Włodarczyk, Aleksandra, et al.
Publicado: (2021)

Eosinophilic Esophagitis—What Do We Know So Far?
por: Wąsik, Jakub, et al.
Publicado: (2023)

Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF(3)-Phe-Asp]NH(2)
por: Piekielna-Ciesielska, Justyna, et al.
Publicado: (2018)

Ghee Butter from Bovine Colostrum Reduces Inflammation in the Mouse Model of Acute Pancreatitis with Potential Involvement of Free Fatty Acid Receptors
por: Tarasiuk, Aleksandra, et al.
Publicado: (2021)

AdipoRon, an Orally Active, Synthetic Agonist of AdipoR1 and AdipoR2 Receptors Has Gastroprotective Effect in Experimentally Induced Gastric Ulcers in Mice
por: Zatorski, Hubert, et al.
Publicado: (2021)

Clinical and Laboratory Characteristics of Anaemia in Hospitalized Patients with Inflammatory Bowel Disease
por: Woźniak, Małgorzata, et al.
Publicado: (2023)

Clinical Significance of Erythroferrone and Bone Morphogenetic Protein-6 in Patients with Anemia in the Course of Inflammatory Bowel Disease
por: Woźniak, Małgorzata, et al.
Publicado: (2023)

IBS-Symptoms in IBD Patients—Manifestation of Concomitant or Different Entities
por: Szałwińska, Patrycja, et al.
Publicado: (2020)

Chlorogenic acid reduces inflammation in murine model of acute pancreatitis
por: Tarasiuk, Aleksandra, et al.
Publicado: (2021)

Oxidative Stress Does Not Influence Subjective Pain Sensation in Inflammatory Bowel Disease Patients
por: Zielińska, Anna Krystyna, et al.
Publicado: (2021)

Walnut Oil Alleviates Intestinal Inflammation and Restores Intestinal Barrier Function in Mice
por: Bartoszek, Adrian, et al.
Publicado: (2020)

Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives
por: Sobczak, Marta, et al.
Publicado: (2013)

Current concepts in the pathogenesis of cryptoglandular perianal fistula
por: Włodarczyk, Marcin, et al.
Publicado: (2021)

Efficacy, Safety and Future Perspectives of JAK Inhibitors in the IBD Treatment
por: Dudek, Patrycja, et al.
Publicado: (2021)

A Crosstalk between the Cannabinoid Receptors and Nociceptin Receptors in Colitis—Clinical Implications
por: Wołyniak, Maria, et al.
Publicado: (2022)

Current Overview on Clinical Management of Chronic Constipation
por: Włodarczyk, Jakub, et al.
Publicado: (2021)

Current Overview on the Use of Mesenchymal Stem Cells for Perianal Fistula Treatment in Patients with Crohn’s Disease
por: Włodarczyk, Marcin, et al.
Publicado: (2021)

Clinical potential of eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome
por: Sobolewska-Włodarczyk, Aleksandra, et al.
Publicado: (2016)

New Class of Anti-Inflammatory Therapeutics Based on Gold (III) Complexes in Intestinal Inflammation–Proof of Concept Based on In Vitro and In Vivo Studies
por: Krajewska, Julia B., et al.
Publicado: (2021)

A New Gold(III) Complex, TGS 703, Shows Potent Anti-Inflammatory Activity in Colitis via the Enzymatic and Non-Enzymatic Antioxidant System—An In Vitro, In Silico, and In Vivo Study
por: Włodarczyk, Jakub, et al.
Publicado: (2023)

Short-chain fatty acids–microbiota crosstalk in the coronavirus disease (COVID-19)
por: Włodarczyk, Jakub, et al.
Publicado: (2022)

Endogenous Opioid Imbalance as a Potential Factor Involved in the Pathogenesis of Chronic Kidney Disease-Associated Pruritus in Dialysis Patients
por: Wala-Zielińska, Kamila, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l9qo28s7flispaib78rsao9qnq